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Merck
CN

810219P

Avanti

C12-NBD Sphingomyelin

Avanti Research - A Croda Brand

别名:

N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sphingosine-1-phosphocholine

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关于此项目

经验公式(希尔记法):
C41H73N6O9P
化学文摘社编号:
分子量:
825.03
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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产品名称

C12-NBD Sphingomyelin, Avanti Research - A Croda Brand 810219P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810219P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand 810219P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[P](=O)([O-])(OC[C@H](NC(=O)CCCCCCCCCCCNc1c2n[o]nc2c(cc1)[N+](=O)[O-])[C@H](O)\C=C\CCCCCCCCCCCCC)OCC[N+](C)(C)C

InChI

1S/C41H73N6O9P/c1-5-6-7-8-9-10-11-12-13-15-18-21-24-27-38(48)36(34-55-57(52,53)54-33-32-47(2,3)4)43-39(49)28-25-22-19-16-14-17-20-23-26-31-42-35-29-30-37(46(50)51)41-40(35)44-56-45-41/h24,27,29-30,36,38,48H,5-23,25-26,28,31-34H2,1-4H3,(H2-,42,43,45,49,52,

InChI key

FCQMKLRMKNYONQ-YPGNEAGUSA-N

General description

C12-NBD Sphingomyelin is a fluorescent analog of biologically active molecule, sphingomyelin. Sphingomyelin is predominantly found in the animal plasma membrane. It is abundantly present as component of cell membranes in mammals, nematodes, protozoa.

Application

C12-NBD-sphingomyelin has been used as a substrate to test substrate specificity of neutral ceramidase orthologue encoded by AsahA gene.

Biochem/physiol Actions

Sphingomyelin (SM) is produced from phosphatidylcholine and ceramide on the cell surface and in lumen of the Golgi. SM′s high packing density and affinity to sterols form a rigid barrier to the extracellular environment. SM is also involved in the formation of lipid rafts in cell membranes, which perform important functions in signal transduction and membrane trafficking.

Packaging

5 mL Amber Glass Screw Cap Vial (810219P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


存储类别

11 - Combustible Solids



历史批次信息供参考:

分析证书(COA)

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