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经验公式(希尔记法):
C41H73N6O9P
化学文摘社编号:
分子量:
825.03
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
C12-NBD Sphingomyelin, Avanti Research™ - A Croda Brand 810219P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810219P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810219P
shipped in
dry ice
storage temp.
−20°C
SMILES string
[P](=O)([O-])(OC[C@H](NC(=O)CCCCCCCCCCCNc1c2n[o]nc2c(cc1)[N+](=O)[O-])[C@H](O)\C=C\CCCCCCCCCCCCC)OCC[N+](C)(C)C
InChI
1S/C41H73N6O9P/c1-5-6-7-8-9-10-11-12-13-15-18-21-24-27-38(48)36(34-55-57(52,53)54-33-32-47(2,3)4)43-39(49)28-25-22-19-16-14-17-20-23-26-31-42-35-29-30-37(46(50)51)41-40(35)44-56-45-41/h24,27,29-30,36,38,48H,5-23,25-26,28,31-34H2,1-4H3,(H2-,42,43,45,49,52,
InChI key
FCQMKLRMKNYONQ-YPGNEAGUSA-N
General description
C12-NBD Sphingomyelin is a fluorescent analog of biologically active molecule, sphingomyelin. Sphingomyelin is predominantly found in the animal plasma membrane. It is abundantly present as component of cell membranes in mammals, nematodes, protozoa.
Application
C12-NBD-sphingomyelin has been used as a substrate to test substrate specificity of neutral ceramidase orthologue encoded by AsahA gene.
Biochem/physiol Actions
Sphingomyelin (SM) is produced from phosphatidylcholine and ceramide on the cell surface and in lumen of the Golgi. SM′s high packing density and affinity to sterols form a rigid barrier to the extracellular environment. SM is also involved in the formation of lipid rafts in cell membranes, which perform important functions in signal transduction and membrane trafficking.
Packaging
5 mL Amber Glass Screw Cap Vial (810219P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
11 - Combustible Solids