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810258E

Avanti

C11 TopFluor™ GM3

Avanti Research™ - A Croda Brand

Synonym(s):

C11 TopFluor GM3 Ganglioside (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C65H110BF2N5O21
CAS Number:
2260795-48-8
Molecular Weight:
1346.40
MDL number:
MFCD00066515
NACRES:
NA.25
UNSPSC Code:
12352211
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Product Name

C11 TopFluor™ GM3, Avanti Research™ - A Croda Brand 810258E, ethanol solution

assay

>99% (TLC)

form

ethanol solution

packaging

pkg of 1 × 1 mL (810258E-100ug)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810258E

concentration

0.1 mg/mL (810258E-100ug)

shipped in

dry ice

storage temp.

−20°C

General description

C11 TopFluor™ GM3 is a fluorescent analog of ganglioside GM3 (Siaa2-3Galb1-4Glcb1-1Cer).

Application

C11 TopFluor™ GM3 has been used to visualize GM3 present in UGCG-KO1.3 cells by immunofluorescence microscopy.

Biochem/physiol Actions

Gangliosides function as modulators in regulating various receptor functions, involved in transmembrane signaling. GM3 plays an important role as a metabolic precursor for the formation of more complex gangliosides. It comprises between 80% and 90% of total ganglioside content in liver and adipose tissue, respectively. Additionally, GM3 is known to promote the subcellular redistribution of major caveolin enriched microdomain (CEM) components coordinating signal transduction. The increased levels of ganglioside GM3 in serum is reported in hyperlipidaemic, hyperglycaemic and type 2 diabetic patients.

Packaging

5 mL Amber Glass Screw Cap Vial (810258E-100ug)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Codes

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

WGK

WGK 1

Flash Point (°F)

55.4 °F - closed cup

Flash Point (°C)

13.0 °C - closed cup

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