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关于此项目
经验公式（希尔记法）:
C65H110BF2N5O21
化学文摘社编号:
分子量:
1346.40
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
产品名称
C11 TopFluor™ GM3, Avanti Research™ - A Croda Brand 810258E, ethanol solution
assay
>99% (TLC)
form
ethanol solution
packaging
pkg of 1 × 1 mL (810258E-100ug)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810258E
concentration
0.1 mg/mL (810258E-100ug)
shipped in
dry ice
storage temp.
−20°C
General description
C11 TopFluor™ GM3 is a fluorescent analog of ganglioside GM3 (Siaa2-3Galb1-4Glcb1-1Cer).
Application
C11 TopFluor™ GM3 has been used to visualize GM3 present in UGCG-KO1.3 cells by immunofluorescence microscopy.
Biochem/physiol Actions
Gangliosides function as modulators in regulating various receptor functions, involved in transmembrane signaling. GM3 plays an important role as a metabolic precursor for the formation of more complex gangliosides. It comprises between 80% and 90% of total ganglioside content in liver and adipose tissue, respectively. Additionally, GM3 is known to promote the subcellular redistribution of major caveolin enriched microdomain (CEM) components coordinating signal transduction. The increased levels of ganglioside GM3 in serum is reported in hyperlipidaemic, hyperglycaemic and type 2 diabetic patients.
Packaging
5 mL Amber Glass Screw Cap Vial (810258E-100ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Disclaimer
Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 1
flash_point_f
55.4 °F - closed cup
flash_point_c
13.0 °C - closed cup