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Merck
CN

810331P

Avanti

18:1 Pyrene PE

Avanti Research - A Croda Brand

Synonym(s):

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(1-pyrenesulfonyl) (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C57H89N2O10PS
CAS Number:
Molecular Weight:
1025.36
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
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Product Name

18:1 Pyrene PE, Avanti Research - A Croda Brand, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (810331P-1mg)

manufacturer/tradename

Avanti Research - A Croda Brand

lipid type

fluorescent lipids

shipped in

dry ice

storage temp.

−20°C

General description

Pyrene is made up of four fused benzol rings. It is an apolar molecule. Phosphatidylethanolamine (PE), a phospholipid is found abundantly in mammalian cells. In mammals, 15-25% of the total lipid comprises of PE. It is enriched in the inner leaflet of membranes and is abundant in the inner mitochondrial membrane.

Application

18:1 Pyrene PE may be used:
  • as a quencher of protein intrinsic emission in intrinsic tryptophan quenching assays of membrane proximity
  • to incorporate in vesicle membranes
  • to label vesicles to confirm the presence of hybrid vesicles in flow-cytometric analysis

Biochem/physiol Actions

Phosphatidylethanolamine (PE) can serve as a lipid chaperone that supports in the folding of membrane proteins. It plays a key role in the activity of respiratory complexes. PE also participates in the initiation of autophagy.

Packaging

5 mL Amber Glass Screw Cap Vial (810331P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids



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beta-Carotene-Lipid Interactions in Liposomes with Different Lipid Composition
Advances in pharmacognosy and phytomedicine, 14, 293-307 (2011)
Ethanolamine and phosphatidylethanolamine: partners in health and disease
Patel D and Witt SN
Oxidative Medicine and Cellular Longevity (2017)
Hybrid, Nanoscale Phospholipid/Block Copolymer Vesicles
Lim SK, et al.
Polymers, 5(3), 1102-1114 (2020)



Global Trade Item Number

SKUGTIN
810331P-1MG04061835190683