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About This Item
Empirical Formula (Hill Notation):
C30H50NO3
CAS Number:
Molecular Weight:
472.72
NACRES:
NA.25
UNSPSC Code:
12352211
Assay:
>99% (TLC)
Form:
powder
assay
>99% (TLC)
form
powder
composition
(contains 10-15% of the ring-opened ketone, TLC)
packaging
pkg of 1 × 1 mg (810611P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
ESR probes
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@](CC[C@]1([C@](CC=C2C[C@H](CC[C@]32C)O)4[H])[H])([C@]1(CC[C@@]43[H])C)[C@H](C)CCCC5(OCC(C)(C)N5[O])C
InChI
1S/C30H50NO3/c1-20(8-7-15-30(6)31(33)27(2,3)19-34-30)24-11-12-25-23-10-9-21-18-22(32)13-16-28(21,4)26(23)14-17-29(24,25)5/h9,20,22-26,32H,7-8,10-19H2,1-6H3/t20-,22+,23?,24-,25?,26?,28+,29-,30?/m1/s1
InChI key
VPKXVMQRURBFJA-AQHLAHBHSA-N
General description
A new paramagnetic analogue of cholesterol as a tool for studying molecular interactions of genuine cholesterol.
Application
CNO (25-doxyl-cholesterol) has been used in 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) liposomes reconstituted with mammalian translocator protein (mTSPO) (mTSPO:DMPC molar ratio of 1:20) for nuclear magnetic resonance (NMR) experiments.
CNO has been used to study the interactions of membrane proteins with cholesterol.
Biochem/physiol Actions
CNO (25-doxyl-cholesterol) is an analog for native cholesterol. It is used in the preparation of multilamellar vesicles. It is used as a spin-labelled analog of cholesterol.
Packaging
5 mL Amber Glass Screw Cap Vial (810611P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
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