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840433P

Avanti

08:0 PG

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), powder, PG(8:0/8:0)

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About This Item

Empirical Formula (Hill Notation):
C22H42O10PNa
CAS Number:
322647-21-2
Molecular Weight:
520.53
MDL number:
MFCD00674287
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

08:0 PG, Avanti Research™ - A Croda Brand

description

1,2-dioctanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840433P-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[Na+]

InChI

1S/C22H43O10P.Na/c1-3-5-7-9-11-13-21(25)29-17-20(32-22(26)14-12-10-8-6-4-2)18-31-33(27,28)30-16-19(24)15-23;/h19-20,23-24H,3-18H2,1-2H3,(H,27,28);/q;+1/p-1/t19?,20-;/m1./s1

InChI key

RMRPSQXPMWXLAU-TVEITMRYSA-M

General description

Phosphatidylglycerol (PG) carries one phosphate in its headgroup and has two acyl chains, that are esterified to a glycerol. Hence it carry a negative charge.

Application

08:0 PG (1,2-dioctanoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) may be used as a short-/odd-fatty acyl chain analog to spike the lipid mixture for the quantification of a natural lipid mixture (egg PG).

Biochem/physiol Actions

Phosphatidylglycerol (PG) can serve as a specific ligand for 4E10 (neutralizing antibody) in the crystal structures. 08:0 PG serves as cryoprotectant in crystallization studies.

Packaging

5 mL Clear Glass Sealed Ampule (840433P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Articles

Critical Micelle Concentrations (CMCs) - Avanti Research™ Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

Lipid-Protein Interactions in Membranes
The Membranes of Cells (2016)
Adriana Irimia et al.
Immunity, 44(1), 21-31 (2016-01-19)
Numerous studies of the anti-HIV-1 envelope glycoprotein 41 (gp41) broadly neutralizing antibody 4E10 suggest that 4E10 also interacts with membrane lipids, but the antibody regions contacting lipids and its orientation with respect to the viral membrane are unknown. Vaccine immunogens
Tommy Hofmann et al.
Chemistry and physics of lipids, 223, 104782-104782 (2019-06-10)
In recent years, lipid quantification gained importance. In most cases, this is achieved by spiking the lipid mixture with deuterated standard lipids or lipid analogues that differ in chain length when compared with the natural lipid components. Usually, conventional ESI

Global Trade Item Number

SKUGTIN
840433P-10MG04061835228829