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840434P

Avanti

10:0 PG

Avanti Research - A Croda Brand

Synonym(s):

PG(10:0/10:0)

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About This Item

Empirical Formula (Hill Notation):
C26H50O10PNa
CAS Number:
Molecular Weight:
576.63
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

10:0 PG, 1,2-didecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (840434P-25mg), pkg of 1 × 500 mg (840434P-500mg)

manufacturer/tradename

Avanti Research - A Croda Brand 840434P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCCCC)=O)COC(CCCCCCCCC)=O.[Na+]

InChI

1S/C26H51O10P.Na/c1-3-5-7-9-11-13-15-17-25(29)33-21-24(22-35-37(31,32)34-20-23(28)19-27)36-26(30)18-16-14-12-10-8-6-4-2;/h23-24,27-28H,3-22H2,1-2H3,(H,31,32);/q;+1/p-1/t23?,24-;/m1./s1

InChI key

WOGMIDKKARMDEU-RETUOTIWSA-M

General description

Phosphatidylglycerol (PG) is one of the important lipid, found in the membranes of bacteria. But in mammals, PG accounts for only 1–2 mol% of phospholipids. This lipid is abundantly present in the lung surfactant. thus pointing to an important role therein.

Application

10:0 PG (1,2-didecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol)) may be used as a component in the liposomes, labeled with β-pyrene-C10-PG. It may also be used in the preparation of small unilamellar vesicle (SUV) liposomes.

Biochem/physiol Actions

Phosphatidylglycerol (PG) serves as an indicator of lung maturity in fetus.

Packaging

30 mL Amber Wide Mouth Bottle with Screw Cap (840434P-500mg)
5 mL Clear Glass Sealed Ampule (840434P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids



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Articles

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn


Analysis of complex lipidomes
Medical Applications of Mass Spectrometry, 223-249 (2008)
Analysis of complex lipidomes
Medical Applications of Mass Spectrometry, 223-249 (2008)
Alison H Dewald et al.
Biophysical journal, 100(9), 2131-2140 (2011-05-05)
The spontaneous folding of two Neisseria outer membrane proteins, opacity-associated (Opa)(60) and Opa(50) into lipid vesicles was investigated by systematically varying bulk and membrane properties. Centrifugal fractionation coupled with sodium dodecyl sulfate polyacrylamide gel electrophoresis mobility assays enabled the discrimination



Global Trade Item Number

SKUGTIN
840434P-25MG04061835228836