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840475C

Avanti

18:1 (Δ9-Cis) PG

Avanti Polar Lipids

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Synonym(s):
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DOPG; PG(18:1(9Z)/18:1(9Z))
Empirical Formula (Hill Notation):
C42H78O10PNa
CAS Number:
67254-28-8
Molecular Weight:
797.03
NACRES:
NA.25

description

1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt), chloroform solution

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840475C-25mg)
pkg of 2 × 4 mL (840475C-200mg)
pkg of 5 × 4 mL (840475C-500mg)

manufacturer/tradename

Avanti Polar Lipids

concentration

10 mg/mL (840475C-25mg)
25 mg/mL (840475C-200mg)
25 mg/mL (840475C-500mg)

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

General description

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG has two hydroxyl groups in its head group. It is an anionic lipid.

Biochem/physiol Actions

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.

Packaging

5 mL Clear Glass Sealed Ampule (840475C-200mg)
5 mL Clear Glass Sealed Ampule (840475C-25mg)
5 mL Clear Glass Sealed Ampule (840475C-500mg)

also commonly purchased with this product

Product No.
Description
Pricing

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

易制毒化学品（2类）
危险化学品

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Membrane Structure and Dynamics
Cell Biology, 227- 239 (2017)
Lipids
Medical Biochemistry, 99- 119 (2017)
Choosing the right fluorophore for single-molecule fluorescence studies in a lipid environment
Zhang Z, et al.
Biochimica et Biophysica Acta - Biomembranes, 1859(7), 1242- 1253 (2017)
Md Zahidul Islam et al.
Langmuir : the ACS journal of surfaces and colloids, 33(9), 2433-2443 (2017-02-07)
The translocation of cell-penetrating peptides (CPPs) through plasma membranes of living cells is an important physiological phenomenon in biomembranes. To reveal the mechanism underlying the translocation of a CPP, transportan 10 (TP10), through lipid bilayers, we examined the effects of
Mariya Chavarha et al.
Biophysical journal, 104(3), 594-603 (2013-02-28)
The hydrophobic surfactant proteins, SP-B and SP-C, greatly accelerate the adsorption of the surfactant lipids to an air/water interface. Previous studies of factors that affect curvature suggest that vesicles may adsorb via a rate-limiting structure with prominent negative curvature, in
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