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841118C

Avanti

Egg Trans PE

Avanti Research™ - A Croda Brand

Synonym(s):

L-a-Phosphatidylethanolamine Transphosphatidylated (prepared from Egg PC)

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About This Item

CAS Number:
383907-63-9
MDL number:
MFCD00672608
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

Egg Trans PE, L-α-phosphatidylethanolamine, transphosphatidylated (Egg, Chicken), chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (841118C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 841118C

concentration

10 mg/mL (841118C-25mg)

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O

InChI

1S/C39H76NO8P/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-39(42)48-37(36-47-49(43,44)46-34-33-40)35-45-38(41)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,37H,3-16,19-36,40H2,1-2H3,(H,43,44)/b18-17-/t37-/m1/s1

InChI key

FHQVHHIBKUMWTI-OTMQOFQLSA-N

General description

Phosphatidylethanolamine (PE) is a phospholipid found in all living organism. The egg yolk contains high levels of unsaturated PE which accounts to 83.10%. The phosphatidylethanolamine (PE) headgroup is a zwitterion, with a negatively charged phosphate group and positively charged free amine group.

Application

Egg Trans PE is suitable for use:
  • in the incubation of platelets for phospholipid enrichment and quantification by ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)
  • in the synthesis of isoketals-phosphatidylethanolamine (IsoK-PE)
  • in the preparation of phospholipid vesicles for factor X activation studies

Biochem/physiol Actions

Phosphatidylethanolamine (PE) along with other phospholipids forms the backbone of biological membranes. PE is known to regulate autophagy. The autophagic membranes possesses PE with high degree of unsaturation. Egg yolk PE has high radical scavenging activity owing to antioxidant potential.

Packaging

5 mL Clear Glass Sealed Ampule (841118C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

危险化学品
易制毒化学品（2类）

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Analytical characterization of the role of phospholipids in platelet adhesion and secretion
Koseoglu S, et al.
Analytical Chemistry, 87(1), 413-421 (2014)
Isoketals form cytotoxic phosphatidylethanolamine adducts in cells
Sullivan CB, et al.
Journal of Lipid Research, 51(5), 999-1009 (2010)
Factor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake
Bloem E, et al.
Journal of biological and chemical chronicles, 288(41), 29670-29679 (2013)
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Global Trade Item Number

SKUGTIN
841118C-25MG04061835352098