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850142P

Avanti

16:0-18:1 PI

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol (ammonium salt), powder

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Synonym(s):
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt); POPI; PI(16:0/18:1); 110660
Empirical Formula (Hill Notation):
C43H84NO13P
CAS Number:
Molecular Weight:
854.10
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850142P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (850142P-500ug))

manufacturer/tradename

Avanti Polar Lipids 850142P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@H]1[C@@H]([C@H](O)[C@H](O)[C@@H](O)[C@@H]1O)OP(OC[C@H](OC([C17H33])=O)COC(CCCCCCCCCCCCCCC)=O)([O-])=O.[NH4+]

General description

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Phosphatidylinositol (PI) carries myo-inositol in its headgroup. This phospholipid comprises up to 10% of the lipid of eukaryotic cells.

Application

16:0-18:1 PI (1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoinositol (ammonium salt)) has been used as a component in giant unilamellar vesicles (GUVs). It has also been sued as a lipid standard in the optimization of the liquid chromatography−mass spectrometry (LC-MS) method conditions.

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (850142P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850142P-500ug)

also commonly purchased with this product

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available


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Inositol Phosphate Metabolism
Cellular and Molecular Mechanisms of Inflammation, 153-174 null
Lipid Protein Interactions in Membranes
Yeagle, PL
The Membranes of Cells, 291-334 null
Sarah N Sipe et al.
Analytical chemistry, 92(1), 899-907 (2019-11-26)
Development of chemical chaperones to solubilize membrane protein complexes in aqueous solutions has allowed for gas-phase analysis of their native-like assemblies, including rapid evaluation of stability and interacting partners. Characterization of protein primary sequence, however, has thus far been limited.
Dorotea Fracchiolla et al.
The Journal of cell biology, 219(7) (2020-05-22)
Autophagy degrades cytoplasmic cargo by its delivery to lysosomes within double membrane autophagosomes. Synthesis of the phosphoinositide PI(3)P by the autophagic class III phosphatidylinositol-3 kinase complex I (PI3KC3-C1) and conjugation of ATG8/LC3 proteins to phagophore membranes by the ATG12-ATG5-ATG16L1 (E3)
Na Li et al.
Analytical chemistry, 91(24), 15873-15882 (2019-11-14)
The matrix plays a prominent role in expanding the ability of matrix assisted laser desorption/ionization mass spectrometry (MALDI MS). However, on account of the unclarity of necessary properties of the matrix in MALDI MS, development of a new matrix is

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