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Merck
CN

850312P

Avanti

DOCPe

Avanti Research - A Croda Brand

Synonym(s):

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethyl phosphate

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About This Item

Empirical Formula (Hill Notation):
C45H86NO8P
CAS Number:
Molecular Weight:
800.14
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

DOCPe, Avanti Research - A Croda Brand 850312P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 200 mg (850312P-200mg), pkg of 1 × 25 mg (850312P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850312P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(CCOP([O-])(OCC)=O)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C45H86NO8P/c1-6-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-44(47)51-42-43(41-46(4,5)39-40-53-55(49,50)52-8-3)54-45(48)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-7-2/h21-24,43H,6-20,25-42H2,1-5H3/b23-21-,24-22-

InChI key

WDTDXEZJIUAULM-SXAUZNKPSA-N

General description

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethylphosphate (DOCPe) is a neutrally charged lipid.
Inverse-phosphocholine lipids, a remix of a common phospholipid, contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Therefore iPC lipids afford a unique opportunity to investigate the biophysical and bioactivity-related ramifications of a charge inversion at the bilayer surface.

Application

DOCPe is suitable for liposomes preparation.

Packaging

20 mL Clear Glass Screw Cap Vial (850312P-200mg)
5 mL Clear Glass Sealed Ampule (850312P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids



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