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850358C

Avanti

16:1 (Δ9-Cis) PC

1,2-dipalmitoleoyl-sn-glycero-3-phosphocholine, chloroform

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Synonym(s):
1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine; PC(16:1(9Z)/16:1(9Z))
Empirical Formula (Hill Notation):
C40H76NO8P
CAS Number:
4724-96-3
Molecular Weight:
730.01
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850358C-25mg)
pkg of 2 × 4 mL (850358C-200mg)

manufacturer/tradename

Avanti Polar Lipids 850358C

concentration

10 mg/mL (850358C-25mg)
25 mg/mL (850358C-200mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

General description

16:1 (Δ9-Cis) PC (1,2-dipalmitoleoyl-sn-glycero-3-phosphocholine) is a lipid derivative having a phosphocholine backbone. It also has two palmitic acid chains each having one cis double bond at 9th carbon. It is a double mono-unsaturated lipid.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

16:1 (Δ9-Cis) PC (1,2-dipalmitoleoyl-sn-glycero-3-phosphocholine) has been used in liposome preparation. It may be used to prepare giant unilamellar vesicles (GUVs) and multilamellar vesicles (MLVs).

Biochem/physiol Actions

Phosphatidylcholine (PC) forms a hydrophobic surface in the mucus by acting as a surfactant resulting in the inhibition of penetrance of bacteria.

Packaging

5 mL Clear Glass Sealed Ampule (850358C-200mg)
5 mL Clear Glass Sealed Ampule (850358C-25mg)

also commonly purchased with this product

Product No.
Description
Pricing

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

危险化学品
易制毒化学品（2类）

Certificates of Analysis (COA)

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Bilayer thickness and curvature influence binding and insertion of a pHLIP peptide
Karabadzhak AG, et al
Biophysical Journal (2018)
Solubilization of lipids and lipid phases by the styrene-maleic acid copolymer
<BIG><BIG>Pardo JJD, et al</BIG></BIG>
European Biophysics Journal (2017)
Parian AM
Integrative Medicine (2018)
Łukasz Syga et al.
Chembiochem : a European journal of chemical biology, 21(9), 1320-1328 (2019-12-10)
Attachment of lipophilic groups is an important post-translational modification of proteins, which involves the coupling of one or more anchors such as fatty acids, isoprenoids, phospholipids, or glycosylphosphatidyl inositols. To study its impact on the membrane partitioning of hydrophobic peptides
Miranda L Schmidt et al.
Biochimica et biophysica acta. Biomembranes, 1862(5), 183196-183196 (2020-01-21)
Lipid bilayers form the basis of cell membranes and the phase behaviour of the membrane has been linked to proper cell function. Model membranes composed of relatively simple mixtures of phospholipids and cholesterol can already exhibit complex phase behaviour. Specifically

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