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850445P

Avanti

14:0-16:0 PC

Name: 14:0-16:0 PC
Brand: AVANTI

1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine, powder

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Synonym(s):

1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine; MPPC; PC(14:0/16:0)

Empirical Formula (Hill Notation):

C₃₈H₇₆NO₈P

CAS Number:

69525-80-0

Molecular Weight:

705.99

NACRES:

NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (850445P-25mg)
pkg of 1 × 500 mg (850445P-500mg)

manufacturer/tradename

Avanti Polar Lipids 850445P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O)=O

InChI

1S/C38H76NO8P/c1-6-8-10-12-14-16-18-19-21-23-25-27-29-31-38(41)47-36(35-46-48(42,43)45-33-32-39(3,4)5)34-44-37(40)30-28-26-24-22-20-17-15-13-11-9-7-2/h36H,6-35H2,1-5H3/t36-/m1/s1

InChI key

RFVFQQWKPSOBED-PSXMRANNSA-N

General description

Phosphatidylcholines (PCs) are phospholipids, that are abundantly present in the tissues of animal. PCs consist of saturated and unsaturated fatty acids in the sn-1 and sn-2 position respectively.

Application

14:0-16:0 PC (1-myristoyl-2-palmitoyl-sn-glycero-3-phosphocholine) may be used:

in the bilayer membrane to study its miscibility with d-erythro-N-palmitoyl-sphingomyelin (16:0-SM) using differential scanning calorimetry (DSC)
as a negative control in stimulation studies to study its effect on insect immune deficiency (IMD) pathway
in generating Wnt3a liposomes

Biochem/physiol Actions

Phosphatidylcholines (PCs) participates in reducing the level of blood lipid and cholesterol.

Packaging

20 mL Clear Glass Screw Cap Vial (850445P-500mg)

5 mL Amber Glass Screw Cap Vial (850445P-25mg)

Storage Class Code

11 - Combustible Solids

Certificates of Analysis (COA)

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705578-5MG-PW

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1000309185

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Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol

Essentials of Medical Biochemistry, 299-320 (2015)

Miscibility of acyl-chain defined phosphatidylcholines with N-palmitoyl sphingomyelin in bilayer membranes.

Bohdana Térová et al.

Biochimica et biophysica acta, 1667(2), 182-189 (2004-12-08)

In this study we have used differential scanning calorimetry (DSC) to study the miscibility of different saturated phosphatidylcholines (PCs) with D-erythro-N-palmitoyl-sphingomyelin (16:0-SM). Information about the miscibility was obtained by observing the thermotropic phase behavior of binary mixtures of saturated PCs

The lipid homeostasis regulation study of arenobufagin in zebrafish HepG2 xenograft model and HepG2 cells using integrated lipidomics-proteomics approach.

Li-Juan Zhao et al.

Journal of ethnopharmacology, 260, 112943-112943 (2020-05-19)

Arenobufagin (ArBu) is an important anti-tumor ingredient of Chan'su which has long been used as traditional Chinese medicine in clinic for tumor therapy in China. The purpose of our study is to investigate the lipid homeostasis regulation effects of ArBu

Liposomal packaging generates Wnt protein with in vivo biological activity.

Nathan T Morrell et al.

PloS one, 3(8), e2930-e2930 (2008-08-14)

Wnt signals exercise strong cell-biological and regenerative effects of considerable therapeutic value. There are, however, no specific Wnt agonists and no method for in vivo delivery of purified Wnt proteins. Wnts contain lipid adducts that are required for activity and

Effects of different fatty acids composition of phosphatidylcholine on brain function of dementia mice induced by scopolamine.

Miao-Miao Zhou et al.

Lipids in health and disease, 15(1), 135-135 (2016-08-26)

Phosphatidylcholine (PC), the major source of dietary choline, has been demonstrated to improve the capability of learning and memory in rodent and the amelioration of long-chain n-3 polyunsaturated fatty acids (PUFA) on anti-aging and anti-oxidation is widely known as well.

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