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About This Item
Empirical Formula (Hill Notation):
C14H28O6
CAS Number:
Molecular Weight:
292.37
MDL number:
UNSPSC Code:
12161902
NACRES:
NA.25
description
n-octyl-β-D-glucopyranoside
Assay
>99% (contains <0.2% alpha isomer, TLC)
form
powder
mol wt
292.37 g/mol
packaging
pkg of 1 × 1 g (850511P-1g)
pkg of 1 × 5 g (850511P-5g)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@H]1O[C@@H](OCCCCCCCC)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1
InChI key
HEGSGKPQLMEBJL-RKQHYHRCSA-N
General description
n-octyl-β-D-glucoside (βOG) is a non-ionic detergent. It has a eight carbon hydrophobic tail.
Octyl glucoside is a dialyzable nonionic detergent for functional solubilization and purification of membrane proteins.
Application
n-octyl-β-D-glucoside is suitable for use to study its self-diffusion coefficients in α-cyclodextrin and β-cyclodextrin solutions at 25°C.
Biochem/physiol Actions
n-octyl-β-D-glucoside (βOG) helps to extract, solubilize and denature membrane proteins. Octyl glucoside has versatile uses including: reconstituting an ion channel, solubilizing an enzyme and incorporating a protein into liposomes. Also, nonionizing detergent complexes are used in protein crystallization studies. It is mainly used in the expression and purification of recombinant protein.
Packaging
20 mL Clear Glass Screw Cap Vial (850511P-1g)
30 mL Amber Wide Mouth Glass Bottle with Screw Cap (850511P-5g)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
涉药品监管产品
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Interactions between n-octyl and n-nonyl beta-D-glucosides and alpha-and beta-cyclodextrins as seen by self-diffusion NMR
Valente AJM, et al.
Journal of Colloid and Interface Science, 281(1), 218-224 (2005)
A single beta-octyl glucoside molecule induces HIV-1 Nef dimer formation in the absence of partner protein binding
Wu M, et al.
Testing, 13(2), e0192512-e0192512 (2018)
APOBEC3G is incorporated into virus-like particles by a direct interaction with HIV-1 Gag nucleocapsid protein
Alce TM and Popik W
The Journal of Biological Chemistry, 279(33), 34083-34086 (2004)
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