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Merck
CN

850536O

Avanti

8.8 MAG

Avanti Research™ - A Croda Brand

Synonym(s):

1-(8Z-hexadecenoyl)-rac-glycerol

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About This Item

Empirical Formula (Hill Notation):
C19H36O4
CAS Number:
749266-38-4
Molecular Weight:
328.49
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

8.8 MAG, Avanti Research™ - A Croda Brand 850536O

InChI

1S/C19H36O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)23-17-18(21)16-20/h8-9,18,20-21H,2-7,10-17H2,1H3/b9-8-

InChI key

CRXZGWVXXGFOLB-HJWRWDBZSA-N

SMILES string

OCC(O)COC(CCCCCC/C=C\CCCCCCC)=O

assay

>99% (TLC)

form

oil

mol wt

328.49 g/mol

packaging

pkg of 10 × 0.1 g (with screw cap (850536O-1g))
pkg of 1 × 25 mg (with screw cap (850536O-25mg))

manufacturer/tradename

Avanti Research™ - A Croda Brand 850536O

technique(s)

protein sequencing: suitable

shipped in

dry ice

storage temp.

−20°C

Application

8.8 MAG may be used as a host lipid to grow MdfA (multidrug transporter protein)–YN1074 (Fab fragment) complex grown using the lipidic cubic phase (LCP) crystallization method.

Biochem/physiol Actions

Monoacylglycerols are used in lotions, ointments and deodorants. It serves as a lubricant, antistatic and plastifying agent, hence it is very useful in the plastic industry.

General description

Monoacylglycerols (MAGs) are glycerol esters, that can be produced by the glycerolysis of triglycerides and alkyl esters. MAGs are polar lipids and amphiphilic in nature.
This new Lipid detergent may be used for crystallizing membrane proteins by using lipidic mesophases. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that it has been used to solve X-ray crystallographic structures of prokaryotic and eukaryotic proteins, proteins that are monomeric, homo- and hetero-multimeric, chromophore-containing and chromophore-free, and alpha-helical and beta-barrel proteins.

Packaging

5 mL PTFE Vial with Screw Cap (850536O-1g)
5 mL PTFE Vial with Screw Cap (850536O-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available

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An overview of the development and applications of nanoscale materials in the food industry
Nanotechnology in the Food, Beverage and Nutraceutical Industries (2012)
Synthesis and characterization of monoacylglycerols through glycerolysis of ethyl esters derived from linseed oil by green processes
Hobuss CB, et al.
Royal Society of Chemistry Advances, 10, 2327-2336 (2020)
Kumar Nagarathinam et al.
Acta crystallographica. Section F, Structural biology communications, 73(Pt 7), 423-430 (2017-07-12)
The active efflux of antibiotics by multidrug-resistance (MDR) transporters is a major pathway of drug resistance and complicates the clinical treatment of bacterial infections. MdfA is a member of the major facilitator superfamily (MFS) from Escherichia coli and provides resistance
Niklaus Johner et al.
Journal of the American Chemical Society, 136(8), 3271-3284 (2014-02-06)
The recent advances in the in meso crystallization technique for the structural characterization of G-protein coupled receptor (GPCR) proteins have established the usefulness of the lipidic-cubic phases (LCPs) in the field of crystallography of membrane proteins. It is surprising that
Martin Caffrey et al.
Journal of visualized experiments : JoVE, (45) (2010-11-30)
A detailed protocol for crystallizing membrane proteins by using lipidic mesophases is described. This method has variously been referred to as the lipidic cubic phase or in meso method. The method has been shown to be quite versatile in that

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