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850706P

Avanti

16:1 PE

1,2-dipalmitoleoyl-sn-glycero-3-phosphoethanolamine, powder

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Synonym(s):
1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphoethanolamine; PE(16:1(9Z)/16:1(9Z))
Empirical Formula (Hill Notation):
C37H70NO8P
CAS Number:
61599-23-3
Molecular Weight:
687.93
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 2 × 100 mg (850706P-200mg)
pkg of 1 × 25 mg (850706P-25mg)

manufacturer/tradename

Avanti Polar Lipids 850706P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCC/C=C\CCCCCC)=O)COC(CCCCCCC/C=C\CCCCCC)=O

General description

Phosphatidylethanolamine is an aminophospholipid, which is found in eukaryotic and prokaryotic cells. It is one of the most abundant glycerophospholipids in biological membranes. Phosphatidylethanolamine is found in nervous tissue.

Application

16:1 PE has been used to assess the linearity of response of lipid classes. It has also been used as an internal standard for the determination of plasmenyl-PC and plasmenyl-PE of human heart mitochondria using a Bligh -Dyer extraction method.

Biochem/physiol Actions

Phosphatidylethanolamine forms pure lipid structures. It maintains membrane fluidity in eukaryotic cells. Phosphatidylethanolamine plays a critical role in autophagy, cell division and protein folding. It acts as a precursor for the synthesis of various protein modifications. Phosphatidylethanolamine functions as an intermediate for the synthesis of glycerophospholipid classes.

Packaging

5 mL Clear Glass Sealed Ampule (850706P-200mg)
5 mL Clear Glass Sealed Ampule (850706P-25mg)

Storage Class Code

11 - Combustible Solids

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The Membranes of Cells (2016)
An Introduction to Biological Membranes: Composition, Structure and Function (2016)
High-Throughput Plasma Lipidomics: Detailed Mapping of the Associations with Cardiometabolic Risk Factors
Huynh K, et al.
Cell Chemical Biology, 26(1), 71-84 (2019)
Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei
Farine L, et al.
Scientific reports, 5, 16787-16787 (2015)
Cytochrome c is an oxidative stress-activated plasmalogenase that cleaves plasmenylcholine and plasmenylethanolamine at the sn-1 vinyl ether linkage
Jenkins CM, et al.
The Journal of Biological Chemistry, 293(22), 8693-8709 (2018)
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