Merck
CN
All Photos(1)

Documents

860525P

Avanti

C24:1 Ceramide (d18:1/24:1(15Z))

Avanti Polar Lipids

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
N-nervonoyl-D-erythro-sphingosine
Empirical Formula (Hill Notation):
C42H81NO3
CAS Number:
54164-50-0
Molecular Weight:
648.10
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (860525P-10mg)
pkg of 1 × 25 mg (860525P-25mg)
pkg of 1 × 5 mg (860525P-5mg)
pkg of 1 × 50 mg (860525P-50mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C42H81NO3/c1-3-5-7-9-11-13-15-17-18-19-20-21-22-23-24-26-28-30-32-34-36-38-42(46)43-40(39-44)41(45)37-35-33-31-29-27-25-16-14-12-10-8-6-4-2/h17-18,35,37,40-41,44-45H,3-16,19-34,36,38-39H2,1-2H3,(H,43,46)/b18-17-,37-35+/t40-,41+/m0/s1

InChI key

VJSBNBBOSZJDKB-KPEYJIHVSA-N

General description

Ceramides comprise spingolipids with acyl chains of C14 to C24 saturated and monounsaturated fatty acids. They are present in most of the mammalian tissues.

Application

C24:1 Ceramide (d18:1/24:1(15Z)) has been used as an internal stand in liquid chromatography-mass spectrometer. It is also suitable for use as a standard in high-performance liquid chromatography/tandem mass spectrometry.

Biochem/physiol Actions

Ceramide (d18:1/24:1[15Z]) levels are elevated inprimary open angle glaucoma (POAG). It is a biomarker for the human arterial tissue and plasma major adverse cardiac and cerebrovascular events (MACE). In general, ceramides are key second messengers in sphingomyelin pathway and modulate the pathophysiology of metabolic diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (860525P-10mg)
5 mL Amber Glass Screw Cap Vial (860525P-25mg)
5 mL Amber Glass Screw Cap Vial (860525P-50mg)
5 mL Amber Glass Screw Cap Vial (860525P-5mg)

also commonly purchased with this product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Plasma ceramides as prognostic biomarkers and their arterial and myocardial tissue correlates in acute myocardial infarction
de Carvalho LP, et al.
JACC. Basic to translational science, 3(2), 163-175 (2018)
Atypical surface behavior of ceramides with nonhydroxy and 2-hydroxy very long-chain (C28-C32) PUFAs
Penalva DA, et al.
Biochimica et Biophysica Acta - Biomembranes, 1838(3), 731-738 (2014)
Human trabecular meshwork sphingolipid and ceramide profiles and potential latent fungal commensalism
Aljohani AJ, et al.
Investigative Ophthalmology & Visual Science, 55(6), 3413-3422 (2014)
Hypothalamic AMPK-ER stress-JNK1 axis mediates the central actions of thyroid hormones on energy balance
Martinez-Sanchez N, et al.
Cell Metabolism, 26(1), 212-229 (2017)
Increased ceramide content and NFkappaB signaling may contribute to the attenuation of anabolic signaling after resistance exercise in aged males
Rivas DA, et al.
Journal of Applied Physiology, 113(11), 1727-1736 (2012)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service