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860562P

Avanti

18:1-12:0 Biotin PE

Name: 18:1-12:0 Biotin PE
Brand: AVANTI

Avanti Polar Lipids 860562P, powder

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Synonym(s):

1-oleoyl-2-(12-biotinyl(aminododecanoyl))-sn-glycero-3-phosphoethanolamine

Empirical Formula (Hill Notation):

C₄₅H₈₃N₄O₁₀PS

CAS Number:

799812-67-2

Molecular Weight:

903.20

NACRES:

NA.25

form

powder

packaging

pkg of 1 × 1 mg (860562P-1mg)

manufacturer/tradename

Avanti Polar Lipids 860562P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OCC[NH3+])=O)(OC(CCCCCCCCCCCNC(CCCC[C@]1([H])SC[C@@]2([H])[C@]1([H])NC(N2)=O)=O)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C45H83N4O10PS/c1-2-3-4-5-6-7-8-9-10-11-12-14-17-20-23-30-42(51)56-35-38(36-58-60(54,55)57-34-32-46)59-43(52)31-24-21-18-15-13-16-19-22-27-33-47-41(50)29-26-25-28-40-44-39(37-61-40)48-45(53)49-44/h9-10,38-40,44H,2-8,11-37,46H2,1H3,(H,47,50)(H,54,55)(H2,48,49,53)/b10-9-/t38-,39+,40+,44+/m1/s1

InChI key

HACDNRDNASOHSM-IBTAXAMTSA-N

Application

18:1-12:0 Biotin PE or 1-oleoyl-2-(12-biotinyl(aminododecanoyl))-sn-glycero-3-phosphoethanolamine has been used during the liposome preparation to make liposomes detectable during standard flow cytometry. It is also suitable for labelling phospholipid vesicles.

Biochem/physiol Actions

1-oleoyl-2-(12-biotinyl(aminododecanoyl))-sn-glycero-3-phosphoethanolamine or biotin PE is majorly used in the formation of lipid vesicle in supported lipid bilayer.

Packaging

5 mL Clear Glass Sealed Ampule (860562P-1mg)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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ProLIF-quantitative integrin protein-protein interactions and synergistic membrane effects on proteoliposomes

De Franceschi N, et al.

Journal of Cell Science, 132(4), 3938-3946 (2019)

TIRF imaging of Fc gamma receptor microclusters dynamics and signaling on macrophages during frustrated phagocytosis

Lin J, et al.

BMC Immunology, 17(1), 5-5 (2016)

Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity

Meems H, et al.

Blood, 114(18), 3938-3946 (2009)

Binding Cooperativity Matters: A GM1-Like Ganglioside-Cholera Toxin B Subunit Binding Study Using a Nanocube-Based Lipid Bilayer Array.

Nolan C Worstell et al.

PloS one, 11(4), e0153265-e0153265 (2016-04-14)

Protein-glycan recognition is often mediated by multivalent binding. These multivalent bindings can be further complicated by cooperative interactions between glycans and individual glycan binding subunits. Here we have demonstrated a nanocube-based lipid bilayer array capable of quantitatively elucidating binding dissociation

Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change.

Matthew Brecher et al.

Journal of virology, 86(1), 364-372 (2011-10-28)

Cellular entry of Ebola virus (EBOV), a deadly hemorrhagic fever virus, is mediated by the viral glycoprotein (GP). The receptor-binding subunit of GP must be cleaved (by endosomal cathepsins) in order for entry and infection to proceed. Cleavage appears to

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