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860652P

Avanti

C8 Ceramide-1-Phosphate (d17:1/8:0)

Avanti Research™ - A Croda Brand

Synonym(s):

N-octanoyl-ceramide-1-phosphate (C17 base) (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C25H53N2O6P
CAS Number:
474944-04-2
Molecular Weight:
508.67
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

C8 Ceramide-1-Phosphate (d17:1/8:0), Avanti Research™ - A Croda Brand 860652P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860652P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 860652P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@@]([H])(NC(CCCCCCC)=O)COP([O-])(O)=O.[NH4+]

InChI key

QZINIJMZYDYICQ-ITEYRTANSA-N

General description

C8 Ceramide-1-Phosphate (d17:1/8:0) is a novel bioactive sphingolipid. It is formed by the phosphorylation of C8-ceramide or N-octanoyl-D-erythro-sphingosine (C17 base) catalyzed by ceramide kinase (CERK). C1P is a sphingolipid analog of phosphatidate.

Biochem/physiol Actions

Ceramide 1-phosphate (C1P) acts as a mitogenic agent. It exhibits antiapoptotic and prosurvival properties. C1P stimulates inflammatory response and facilitates phagocytosis. It also has an ability to negatively regulate tumor necrosis factor-α (TNFα) production induced by lipopolysaccharide. C1P is reputed to be a second lipid messenger of agonist-stimulated sphingomyelin metabolism.

Packaging

5 mL Amber Glass Screw Cap Vial (860652P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

WGK

WGK 3

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