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860685P

Avanti

Lyso-SM-d9

Avanti Research™ - A Croda Brand

Synonym(s):

Sphingosylphosphorylcholine-d9

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About This Item

Empirical Formula (Hill Notation):
C23H40D9N2O5P
CAS Number:
2315262-28-1
Molecular Weight:
473.67
MDL number:
MFCD35061233
UNSPSC Code:
12352211
NACRES:
NA.12
Assay:
99% (TLC)
Form:
powder
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Product Name

Lyso-SM-d9, powder, Avanti Research™ - A Croda Brand (860685P)

assay

99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860685P-1MG)

manufacturer/tradename

Avanti Research™ - A Croda Brand (860685P)

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(N)COP([O-])(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O

InChI

1S/C23H49N2O5P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)22(24)21-30-31(27,28)29-20-19-25(2,3)4/h17-18,22-23,26H,5-16,19-21,24H2,1-4H3/b18-17+/t22-,23+/m0/s1/i2D3,3D3,4D3

InChI key

JLVSPVFPBBFMBE-IQSZTMPESA-N

General description

Lyso-SM-d9 is a deuterated lyso-SM. Lyso sphingomyelin (Lyso-SM) is obtained from sphingomyelin due to the cleavage of N-acyl linkage of ceramides in sphingomyelin by the help of hydrolase.

Biochem/physiol Actions

Lyso sphingomyelin (Lyso-SM) functions as lipid mediators. It plays a vital role in cellular functioning of the skin, blood vessels, brain and heart. It also helps in the functioning of the immune system.

Packaging

5 mL Amber Glass Screw Cap Vial

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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A novel enzyme that cleaves the N-acyl linkage of ceramides in various glycosphingolipids as well as sphingomyelin to produce their lyso forms.
Ito M
The Journal of Biological Chemistry, 270(41), 24370-24374 (1995)
Lyso-sphingomyelin is elevated in dried blood spots of Niemann-Pick B patients
Chuang W L, et al.
Molecular Genetics and Metabolism, 111(2), 209-211 (2014)