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860821P

Avanti

22:0(2R-OH) Ceramide

Name: 22:0(2R-OH) Ceramide
Brand: AVANTI

Avanti Research^™ - A Croda Brand

Synonym(s):

N-(2′-(R)-hydroxybehenoyl)-D-erythro-sphingosine

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About This Item

Empirical Formula (Hill Notation):

C₄₀H₇₉NO₄

CAS Number:

31417-10-4

Molecular Weight:

638.06

MDL number:

MFCD22416677

UNSPSC Code:

12352211

NACRES:

NA.25

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Properties

Product Name

22:0(2R-OH) Ceramide, Avanti Research^™ - A Croda Brand 860821P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (860821P-5mg)

manufacturer/tradename

Avanti Research^™ - A Croda Brand 860821P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC([C@H](O)CCCCCCCCCCCCCCCCCCCC)=O)CO

InChI key

FCCZDEAAQZWMGI-ZAKDXXNHSA-N

Description

General description

Hydroxy fatty acid (hFA)-sphingolipids are highly found in the myelin sheath. 2-hydroxy fatty acids (hFA) ceramides are present in the surface epithelium of the skin. 22:0(2R-OH) Ceramide is a unique ceramide containing 22C long chain base fatty acid (behenic acid)-with 2′-hydroxyl group in R configuration.

Biochem/physiol Actions

Hydroxy fatty acid (hFA)-sphingolipids play a vital role in cell signaling, cell differentiation and apoptosis. They also help in formation and function of myelin. Ceramides containing hydroxy fatty acid are synthesized by NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H). These hFA-sphingolipids facilitate the epidermal permeability barrier function.

Packaging

5 mL Amber Glass Screw Cap Vial (860821P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk

WGK 3

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