Skip to Content
Merck
CN

868516P

Avanti

16:0-d31 Ceramide

Avanti Research™ - A Croda Brand

Synonym(s):

N-palmitoyl-d31-D-erythro-sphingosine

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C34H36NO3D31
CAS Number:
852043-41-5
Molecular Weight:
569.09
MDL number:
MFCD22416906
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

16:0-d31 Ceramide, Avanti Research™ - A Croda Brand 868516P, powder

InChI key

YDNKGFDKKRUKPY-MFTNTAGNSA-N

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)CO

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (868516P-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 868516P

shipped in

dry ice

storage temp.

−20°C

General description

Ceramide is a N-acylsphingosine derived mainly from sphingomyelin (SM) or sphingosine (Sph) by acidic sphingomyelinase (ASMase) during sphingolipid (SPL) biosynthesis and degradation pathways. It is a mostly studied SPL mediator.

Application

16:0-d31 Ceramide is suitable for use as an internal standard for quantification of N-palmitoyl-D-erythro-sphingosine (C16-ceramide) levels by liquid chromatography/mass spectrometry (LC-MS).

Biochem/physiol Actions

Ceramide plays an important role in various processes including, cellular differentiation, apoptosis and cell signaling pathways.

Packaging

5 mL Amber Glass Screw Cap Vial (868516P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lithocholic acid disrupts phospholipid and sphingolipid homeostasis leading to cholestasis in mice
Matsubara T, et al.
Hepatology, 53(4), 1282-1293 (2011)
Ambika T Singh et al.
Molecular and cellular endocrinology, 362(1-2), 48-59 (2012-06-02)
Sphingolipid mediators such as ceramide are pleiotropic regulators of cellular growth, differentiation and apoptosis. We investigated the role of ceramide biosynthesis, metabolism and actions in term human cytotrophoblasts syncytialized over 7 days in culture. Intracellular C16 ceramide levels increased modestly
Enhancing cardiac triacylglycerol metabolism improves recovery from ischemic stress
Kolwicz SC, et al.
Molecular and Cellular Endocrinology, 64(8), 2817-2827 (2015)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service