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Merck
CN

870454O

Avanti

2-AG-d11

Avanti Research™ - A Croda Brand

Synonym(s):

2-arachidonoyl glycerol-d11

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About This Item

Empirical Formula (Hill Notation):
C23H27D11O4
CAS Number:
2260670-54-8
Molecular Weight:
389.61
MDL number:
MFCD00133427
UNSPSC Code:
12352100
NACRES:
NA.25

Key Documents

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Product Name

2-AG-d11, Avanti Research™ - A Croda Brand 870454O

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mg (with screw cap/argon/foil bag (870454O-1mg))

manufacturer/tradename

Avanti Research™ - A Croda Brand 870454O

shipped in

dry ice

storage temp.

−20°C

General description

2-Arachidonoylglycerol (2-AG) is an arachidonic acid-containing monoacylglycerol. It is a potent endogenous ligand for cannabinoid receptors. 2-AG is found in the brain and hematopoietic cells, such as macrophages, lymphocytes and platelets.

Biochem/physiol Actions

2-Arachidonoylglycerol (2-AG) functions as an agonist of cannabinoid receptors. It weakens synaptic transmission and acts as a neuromodulator. It has cytoprotective activity. 2-AG stimulates the activation of p42/44 MAPK (mitogen-activated protein kinase), p38 MAPK and c-Jun N-terminal kinase.

Packaging

5 mL PTFE Vial with Screw Cap/Argon/Foil Bag (870454O-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

10 - Combustible liquids

Flash Point(F)

No data available

Flash Point(C)

No data available

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The Endocannabinoid 2-Arachidonoylglycerol Regulates Platelet Function.
Baldassarri S, et al.
Blood (2006)
2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces rapid actin polymerization in HL-60 cells differentiated into macrophage-like cells
Gokoh M, et al.
The Biochemical Journal, 386(3) (2005)
The Endocannabinoid 2-Arachidonoylglycerol Regulates Platelet Function.
Baldassarri S, et al.
Blood (2006)
Evidence That the Cannabinoid CB1 Receptor Is a 2-Arachidonoylglycerol Receptor Structure-Activity Relationship of 2-Arachidonoylglycerol, Ether-linked Analogues, and Related Compounds
Sugiura T, et al.
The Journal of Biological Chemistry, 274(5) (1999)

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