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Merck
CN

870454O

Avanti

2-AG-d11

Avanti Research - A Croda Brand

别名:

2-arachidonoyl glycerol-d11

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关于此项目

经验公式(希尔记法):
C23H27D11O4
化学文摘社编号:
分子量:
389.61
MDL编号:
UNSPSC代码:
12352100
NACRES:
NA.25
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产品名称

2-AG-d11, Avanti Research - A Croda Brand 870454O

方案

>99% (TLC)

表单

liquid

包装

pkg of 1 × 1 mg (with screw cap/argon/foil bag (870454O-1mg))

制造商/商品名称

Avanti Research - A Croda Brand 870454O

运输

dry ice

储存温度

−20°C

一般描述

2-Arachidonoylglycerol (2-AG) is an arachidonic acid-containing monoacylglycerol. It is a potent endogenous ligand for cannabinoid receptors. 2-AG is found in the brain and hematopoietic cells, such as macrophages, lymphocytes and platelets.

生化/生理作用

2-Arachidonoylglycerol (2-AG) functions as an agonist of cannabinoid receptors. It weakens synaptic transmission and acts as a neuromodulator. It has cytoprotective activity. 2-AG stimulates the activation of p42/44 MAPK (mitogen-activated protein kinase), p38 MAPK and c-Jun N-terminal kinase.

包装

5 mL PTFE Vial with Screw Cap/Argon/Foil Bag (870454O-1mg)

法律信息

Avanti Research is a trademark of Avanti Polar Lipids, LLC

储存分类代码

10 - Combustible liquids

闪点(°F)

No data available

闪点(°C)

No data available


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces rapid actin polymerization in HL-60 cells differentiated into macrophage-like cells
Gokoh M, et al.
The Biochemical Journal, 386(3) (2005)
The Endocannabinoid 2-Arachidonoylglycerol Regulates Platelet Function.
Baldassarri S, et al.
Blood (2006)
Evidence That the Cannabinoid CB1 Receptor Is a 2-Arachidonoylglycerol Receptor Structure-Activity Relationship of 2-Arachidonoylglycerol, Ether-linked Analogues, and Related Compounds
Sugiura T, et al.
The Journal of Biological Chemistry, 274(5) (1999)
The Endocannabinoid 2-Arachidonoylglycerol Regulates Platelet Function.
Baldassarri S, et al.
Blood (2006)

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