870454O
Avanti
2-AG-d11
Avanti Research™ - A Croda Brand
别名:
2-arachidonoyl glycerol-d11
产品名称
2-AG-d11, Avanti Research™ - A Croda Brand 870454O
方案
>99% (TLC)
表单
liquid
包装
pkg of 1 × 1 mg (with screw cap/argon/foil bag (870454O-1mg))
制造商/商品名称
Avanti Research™ - A Croda Brand 870454O
运输
dry ice
储存温度
−20°C
一般描述
2-Arachidonoylglycerol (2-AG) is an arachidonic acid-containing monoacylglycerol. It is a potent endogenous ligand for cannabinoid receptors. 2-AG is found in the brain and hematopoietic cells, such as macrophages, lymphocytes and platelets.
生化/生理作用
2-Arachidonoylglycerol (2-AG) functions as an agonist of cannabinoid receptors. It weakens synaptic transmission and acts as a neuromodulator. It has cytoprotective activity. 2-AG stimulates the activation of p42/44 MAPK (mitogen-activated protein kinase), p38 MAPK and c-Jun N-terminal kinase.
包装
5 mL PTFE Vial with Screw Cap/Argon/Foil Bag (870454O-1mg)
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
储存分类代码
10 - Combustible liquids
闪点(°F)
No data available
闪点(°C)
No data available
2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces rapid actin polymerization in HL-60 cells differentiated into macrophage-like cells
Gokoh M, et al.
The Biochemical Journal, 386(3) (2005)
The Endocannabinoid 2-Arachidonoylglycerol Regulates Platelet Function.
Baldassarri S, et al.
Blood (2006)
Evidence That the Cannabinoid CB1 Receptor Is a 2-Arachidonoylglycerol Receptor Structure-Activity Relationship of 2-Arachidonoylglycerol, Ether-linked Analogues, and Related Compounds
Sugiura T, et al.
The Journal of Biological Chemistry, 274(5) (1999)
The Endocannabinoid 2-Arachidonoylglycerol Regulates Platelet Function.
Baldassarri S, et al.
Blood (2006)
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