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经验公式（希尔记法）:
C23H27D11O4
化学文摘社编号:
分子量:
389.61
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352100
Assay:
>99% (TLC)
Form:
liquid
产品名称
2-AG-d11, Avanti Research™ - A Croda Brand 870454O
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mg (with screw cap/argon/foil bag (870454O-1mg))
manufacturer/tradename
Avanti Research™ - A Croda Brand 870454O
shipped in
dry ice
storage temp.
−20°C
General description
2-Arachidonoylglycerol (2-AG) is an arachidonic acid-containing monoacylglycerol. It is a potent endogenous ligand for cannabinoid receptors. 2-AG is found in the brain and hematopoietic cells, such as macrophages, lymphocytes and platelets.
Biochem/physiol Actions
2-Arachidonoylglycerol (2-AG) functions as an agonist of cannabinoid receptors. It weakens synaptic transmission and acts as a neuromodulator. It has cytoprotective activity. 2-AG stimulates the activation of p42/44 MAPK (mitogen-activated protein kinase), p38 MAPK and c-Jun N-terminal kinase.
Packaging
5 mL PTFE Vial with Screw Cap/Argon/Foil Bag (870454O-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
10 - Combustible liquids
flash_point_f
No data available
flash_point_c
No data available
The Endocannabinoid 2-Arachidonoylglycerol Regulates Platelet Function.
Baldassarri S, et al.
Blood (2006)
2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces rapid actin polymerization in HL-60 cells differentiated into macrophage-like cells
Gokoh M, et al.
The Biochemical Journal, 386(3) (2005)
The Endocannabinoid 2-Arachidonoylglycerol Regulates Platelet Function.
Baldassarri S, et al.
Blood (2006)
Evidence That the Cannabinoid CB1 Receptor Is a 2-Arachidonoylglycerol Receptor Structure-Activity Relationship of 2-Arachidonoylglycerol, Ether-linked Analogues, and Related Compounds
Sugiura T, et al.
The Journal of Biological Chemistry, 274(5) (1999)
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