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870510P

Avanti

16:0 CDP DG

Name: 16:0 CDP DG
Brand: AVANTI

Avanti Polar Lipids 870510P, powder

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Synonym(s):

1,2-dipalmitoyl-sn-glycero-3-(cytidine diphosphate) (ammonium salt)

Empirical Formula (Hill Notation):

C₄₄H₈₇N₅O₁₅P₂

CAS Number:

384835-55-6

Molecular Weight:

988.13

NACRES:

NA.25

form

powder

packaging

pkg of 1 × 5 mg (870510P-5mg)

manufacturer/tradename

Avanti Polar Lipids 870510P

lipid type

bioactive lipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)C=C2)=O)O1)([O-])=O)([O-])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C44H81N3O15P2.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-39(48)57-33-36(60-40(49)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)34-58-63(53,54)62-64(55,56)59-35-37-41(50)42(51)43(61-37)47-32-31-38(45)46-44(47)52;;/h31-32,36-37,41-43,50-51H,3-30,33-35H2,1-2H3,(H,53,54)(H,55,56)(H2,45,46,52);2*1H3/t36-,37-,41+,42?,43-;;/m1../s1

InChI key

IAUUMXARBJMHDT-LWJUINKDSA-N

Application

16:0 CDP DG (1,2-dipalmitoyl-sn-glycero-3-(cytidine diphosphate)) may be used in liposome preparation.

Biochem/physiol Actions

16:0 CDP DG (1,2-dipalmitoyl-sn-glycero-3-(cytidine diphosphate)) acts as a substrate for phosphatidylserine synthase (Pss) to produce cytidine 5′?monophosphate. CDP-diacylglycerol is a derivate of diacylglycerol. It serves as a precursor for the synthesis of essential glycerophospholipids such as the phosphatidylinositides. Altered CDP-diacylglycerol signaling might lead to depression.

Packaging

5 mL Amber Glass Screw Cap Vial (870510P-5mg)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Molecular recognition between guanine and cytosine-functionalized nucleolipid hybrid bilayers supported on gold (111) electrodes.

Julia Alvarez-Malmagro et al.

Bioelectrochemistry (Amsterdam, Netherlands), 132, 107416-107416 (2020-01-26)

A hybrid bilayer lipid membrane (hBLM), constructed with a 1-hexadecanethiol self-assembled interior leaflet and a 1,2-dipalmitoyl-sn-glycero-3-cytidine nucleolipid exterior leaflet, was deposited at the surface of a gold (111) electrode. This system was used to investigate the molecular recognition reaction between

Diverse antidepressants increase CDP-diacylglycerol production and phosphatidylinositide resynthesis in depression-relevant regions of the rat brain.

Kimberly R Tyeryar et al.

BMC neuroscience, 9, 12-12 (2008-01-26)

Major depression is a serious mood disorder affecting millions of adults and children worldwide. While the etiopathology of depression remains obscure, antidepressant medications increase synaptic levels of monoamine neurotransmitters in brain regions associated with the disease. Monoamine transmitters activate multiple

Characterization of a Phosphatidylserine Synthase of Vibrio parahaemolyticus.

Ru-Yin Huang et al.

Current microbiology, 77(5), 710-715 (2020-01-04)

Phosphatidylserine synthase (Pss) is involved in the metabolic pathway in phospholipid synthesis in different organisms. In this study, Pss expression in Vibrio parahaemolyticus was verified through liquid chromatography tandem-mass spectrometry. To analyze the characteristics of Pss, the recombinant Pss was

A Steric Gating Mechanism Dictates the Substrate Specificity of a Rab-GEF.

Laura L Thomas et al.

Developmental cell, 48(1), 100-114 (2018-12-12)

Correct localization of Rab GTPases in cells is critical for proper function in membrane trafficking, yet the mechanisms that target Rabs to specific subcellular compartments remain controversial. Guanine nucleotide exchange factors (GEFs) activate and consequently stabilize Rab substrates on membranes

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