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Merck
CN

870520C

Avanti

18:1 CDP DG

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dioleoyl-sn-glycero-3-(cytidine diphosphate) (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C48H91N5O15P2
CAS Number:
799812-77-4
Molecular Weight:
1040.21
MDL number:
MFCD22416913
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

18:1 CDP DG, Avanti Research™ - A Croda Brand 870520C

SMILES string

[H][C@@](COP(OP(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)C=C2)=O)O1)([O-])=O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+]

InChI

1S/C48H85N3O15P2.2H3N/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-43(52)61-37-40(64-44(53)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)38-62-67(57,58)66-68(59,60)63-39-41-45(54)46(55)47(65-41)51-36-35-42(49)50-48(51)56;;/h17-20,35-36,40-41,45-47,54-55H,3-16,21-34,37-39H2,1-2H3,(H,57,58)(H,59,60)(H2,49,50,56);2*1H3/b19-17-,20-18-;;/t40-,41-,45+,46?,47-;;/m1../s1

InChI key

NECNTGAHQCHVGS-BQGZBBTBSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (870520C-5mg)
pkg of 1 × 2.5 mL (870520C-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870520C

concentration

10 mg/mL (870520C-25mg)
5 mg/mL (870520C-5mg)

lipid type

phosphoglycerides
bioactive lipids

shipped in

dry ice

storage temp.

−20°C

Application

18:1 CDP DG is suitable for liposomes preparation.

Biochem/physiol Actions

18:1 CDP DG or 1,2-dioleoyl-sn-glycero-3-(cytidine diphosphate) produces cytidine 5′?monophosphate by the reaction catalyzed by phosphatidylserine synthase (Pss). CDP-diacylglycerol is derived from diacylglycerol. It serves as a precursor in the production of phosphatidylinositides. Unregulated CDP-diacylglycerol signaling may be associated with the depression.

Packaging

5 mL Clear Glass Sealed Ampule (870520C-25mg)
5 mL Clear Glass Sealed Ampule (870520C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Information

易制毒化学品（2类）
危险化学品
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Kimberly R Tyeryar et al.
BMC neuroscience, 9, 12-12 (2008-01-26)
Major depression is a serious mood disorder affecting millions of adults and children worldwide. While the etiopathology of depression remains obscure, antidepressant medications increase synaptic levels of monoamine neurotransmitters in brain regions associated with the disease. Monoamine transmitters activate multiple
Andrew G Reidenbach et al.
Cell chemical biology, 25(2), 154-165 (2017-12-05)
Human COQ8A (ADCK3) and Saccharomyces cerevisiae Coq8p (collectively COQ8) are UbiB family proteins essential for mitochondrial coenzyme Q (CoQ) biosynthesis. However, the biochemical activity of COQ8 and its direct role in CoQ production remain unclear, in part due to lack
Ru-Yin Huang et al.
Current microbiology, 77(5), 710-715 (2020-01-04)
Phosphatidylserine synthase (Pss) is involved in the metabolic pathway in phospholipid synthesis in different organisms. In this study, Pss expression in Vibrio parahaemolyticus was verified through liquid chromatography tandem-mass spectrometry. To analyze the characteristics of Pss, the recombinant Pss was

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