Product Name
DSPE-PEG(2000) Folate, Avanti Research™ - A Croda Brand 880124P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (880124P-1mg), pkg of 1 × 10 mg (880124P-10mg), pkg of 1 × 5 mg (880124P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 880124P
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCCNC(OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO/C=C\NC(CC[C@H](NC(C1=CC=C(NCC(C=N2)=NC3=C2N=C(N)NC3=O)C=C1)=O)C([O-])=O)=O)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C
Application
DSPE-PEG(2000) Folate has been mixed in chloroform for folate-targeted PEGylated liposomes preparation.
Biochem/physiol Actions
Folate offers protection against megaloblastic anaemia during pregnancy.
Packaging
5 mL Amber Glass Screw Cap Vial (880124P-10mg)
5 mL Amber Glass Screw Cap Vial (880124P-1mg)
5 mL Amber Glass Screw Cap Vial (880124P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
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Microfluidic synthesis of PEG-and folate-conjugated liposomes for one-step formation of targeted stealth nanocarriers
Hood RR, et al.
Pharmaceutical Research, 30(6), 1597-1607 (2013)
Folate and human reproduction.
Tamura T and Picciano MF
American Journal of Clinical Nutrition, 83(5), 993-1016 (2006)
Shih-Jiuan Chiu et al.
Journal of controlled release : official journal of the Controlled Release Society, 112(2), 199-207 (2006-03-28)
A novel transferrin receptor (TfR)-targeted liposomal formulation was synthesized and evaluated for the delivery of a phosphorothioate antisense oligodeoxyribonucleotide (ODN) (G3139, oblimerson sodium, or Genasense) to Bcl-2 in K562 leukemia cells. Liposomes composed of DC-Chol/egg PC/PEG-DSPE (25:73.5:1.5, mol/mol/mol) were loaded
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 880124P-5MG | 04061835187492 |
| 880124P-1MG | 04061835187485 |
| 880124P-10MG | 04061835187478 |