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890703C

Avanti

18:0 EPC (Cl Salt)

Name: 18:0 EPC (Cl Salt)
Brand: AVANTI

Avanti Research^™ - A Croda Brand

Synonym(s):

1,2-distearoyl-sn-glycero-3-ethylphosphocholine (chloride salt)

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About This Item

Empirical Formula (Hill Notation):

C₄₆H₉₃NO₈PCl

CAS Number:

328268-13-9

Molecular Weight:

854.66

MDL number:

MFCD22495358

UNSPSC Code:

12352211

NACRES:

NA.25

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Properties

Product Name

18:0 EPC (Cl Salt), Avanti Research^™ - A Croda Brand 890703C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (890703C-25mg)

manufacturer/tradename

Avanti Research^™ - A Croda Brand 890703C

concentration

10 mg/mL (890703C-25mg)

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)OCC.[Cl-]

InChI

1S/C46H93NO8P.ClH/c1-7-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-45(48)51-42-44(43-54-56(50,52-9-3)53-41-40-47(4,5)6)55-46(49)39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-8-2;/h44H,7-43H2,1-6H3;1H/q+1;/p-1/t44-,56?;/m1./s1

InChI key

ZVWMOQRUUFNEHD-UFOBXVRVSA-M

Description

Application

1,2-distearoyl-sn-glycero-3-ethylphosphocholine (18:0 EPC) might be used:

to study its effect on the synergistic antimicrobial action of eugenol against Escherichia coli C600
to test its use in the formation of lipid nanoparticle variants
as a constituent of the microbubble formulation
to prepare lipid monolayer for the study on the nature and orientation of interaction between graphene oxide (GO) and lipid models

Biochem/physiol Actions

Cationic lipids are useful as co-adjuvants to promote the immunogenicity of vaccines. 1,2-distearoyl-sn-glycero-3-ethylphosphocholine (18:0 EPC) is a cationic lipid and is found to upregulate cluster of differentiation (CD)80 and CD86 co-stimulatory molecules. The hydrophilic moiety and the acyl chains of the cationic lipids highly influences their co-stimulatory action.

Packaging

5 mL Clear Glass Sealed Ampule (890703C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Pictograms

GHS06,GHS08

Signal Word

Danger

Hazard Codes

H302,H315,H319,H331,H336,H351,H361d,H372

Precautionary Statements

P201 - P260 - P264 - P280 - P304 + P340 + P311 - P403 + P233

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Flash Point (°F)

does not flash

Flash Point (°C)