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关于此项目
经验公式(希尔记法):
C46H93NO8PCl
化学文摘社编号:
分子量:
854.66
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
产品名称
18:0 EPC (Cl Salt), Avanti Research™ - A Croda Brand
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 25 mg (890703P-25mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
application(s)
advanced drug delivery
lipid type
transfection
cationic lipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)OCC.[Cl-]
InChI
1S/C46H93NO8P.ClH/c1-7-10-12-14-16-18-20-22-24-26-28-30-32-34-36-38-45(48)51-42-44(43-54-56(50,52-9-3)53-41-40-47(4,5)6)55-46(49)39-37-35-33-31-29-27-25-23-21-19-17-15-13-11-8-2;/h44H,7-43H2,1-6H3;1H/q+1;/p-1/t44-,56?;/m1./s1
InChI key
ZVWMOQRUUFNEHD-UFOBXVRVSA-M
Application
1,2-distearoyl-sn-glycero-3-ethylphosphocholine (18:0 EPC) might be used:
- to study its effect on the synergistic antimicrobial action of eugenol against Escherichia coli C600
- to test its use in the formation of lipid nanoparticle variants
- as a constituent of the microbubble formulation
- to prepare lipid monolayer for the study on the nature and orientation of interaction between graphene oxide (GO) and lipid models
Biochem/physiol Actions
Cationic lipids are useful co-adjuvants for promoting the immunogenicity of vaccines. 1,2-distearoyl-sn-glycero-3-ethylphosphocholine (18:0 EPC) is a cationic lipid and is found to upregulate cluster of differentiation (CD)80 and CD86 co-stimulatory molecules. The hydrophilic moiety and the acyl chains of the cationic lipids highly influences their co-stimulatory action.
Packaging
5 mL Amber Glass Screw Cap Vial (890703P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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存储类别
11 - Combustible Solids
wgk
WGK 3