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Merck
CN

890850C

Avanti

18:1 DAP

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-dioleoyl-3-dimethylammonium-propane (DODAP)

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About This Item

Empirical Formula (Hill Notation):
C41H77NO4
CAS Number:
Molecular Weight:
648.05
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

18:1 DAP, Avanti Research™ - A Croda Brand

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (890850C-25mg), pkg of 2 × 4 mL (890850C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

10 mg/mL (890850C-25mg), 25 mg/mL (890850C-200mg)

application(s)

advanced drug delivery

lipid type

transfection
cationic lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(CN(C)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C41H77NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40(43)45-38-39(37-42(3)4)46-41(44)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h19-22,39H,5-18,23-38H2,1-4H3/b21-19-,22-20-

InChI key

NYDLOCKCVISJKK-WRBBJXAJSA-N

General description

18:1 DAP is a cationic lipid. It is a pH sensitive transfection reagent, used for the preparation of cationic liposomes.

Application

18:1 DAP is suitable :
  • as a component of lipid bilayers
  • in the formulation of stable nucleic acid lipid vesicles
  • in the preparation and physicochemical characterization of antisense oligodeoxyribonucleotide (ODN)-containing folate (FA)-targeted or non-targeted liposomes

Packaging

5 mL Clear Glass Sealed Ampule (890850C-200mg)
5 mL Clear Glass Sealed Ampule (890850C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Liver,Kidney, Respiratory system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point (°F)

does not flash

Flash Point (°C)

does not flash



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