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Safety Information

890880C

Avanti

18:0 TAP

1,2-stearoyl-3-trimethylammonium-propane (chloride salt), chloroform

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Synonym(s):
1,2-stearoyl-3-trimethylammonium-propane (chloride salt)
Empirical Formula (Hill Notation):
C42H84NO4Cl
CAS Number:
220609-41-6
Molecular Weight:
702.57
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 2.5 mL (890880C-25mg)
pkg of 2 × 4 mL (890880C-200mg)

manufacturer/tradename

Avanti Polar Lipids 890880C

concentration

10 mg/mL (890880C-25mg)
25 mg/mL (890880C-200mg)

lipid type

transfection
cationic lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Cl-]

Application

18:0 TAP has been used in chloroform to prepare microbubbles.

Packaging

5 mL Clear Glass Sealed Ampule (890880C-200mg)
5 mL Clear Glass Sealed Ampule (890880C-25mg)

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Information

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In vivo transfection and detection of gene expression of stem cells preloaded with DNA-carrying microbubbles
Tavri S, et al.
Radiology, 276(2), 518-525 (2015)
Yuki Takechi-Haraya et al.
Langmuir : the ACS journal of surfaces and colloids, 34(26), 7805-7812 (2018-06-06)
It has recently been recognized that the mechanical properties of lipid nanoparticles play an important role during in vitro and in vivo behaviors such as cellular uptake, blood circulation, and biodistribution. However, there have been no quantitative investigations of the
A E Regelin et al.
Biochimica et biophysica acta, 1464(1), 151-164 (2000-03-08)
In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)

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