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Merck
CN

890880C

Avanti

18:0 TAP

Avanti Research™ - A Croda Brand

别名:

1,2-stearoyl-3-trimethylammonium-propane (chloride salt)

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关于此项目

经验公式（希尔记法）:
C42H84NO4Cl
化学文摘社编号:
220609-41-6
分子量:
702.57
MDL number:
MFCD22495362
UNSPSC Code:
12352211
NACRES:
NA.25

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产品名称

18:0 TAP, 1,2-stearoyl-3-trimethylammonium-propane (chloride salt), chloroform

InChI

1S/C42H84NO4.ClH/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;/h40H,6-39H2,1-5H3;1H/q+1;/p-1

InChI key

NTTZBBIBMSBLNK-UHFFFAOYSA-M

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Cl-]

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (890880C-25mg)
pkg of 2 × 4 mL (890880C-200mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 890880C

concentration

10 mg/mL (890880C-25mg)
25 mg/mL (890880C-200mg)

lipid type

transfection
cationic lipids

shipped in

dry ice

storage temp.

−20°C

Packaging

5 mL Clear Glass Sealed Ampule (890880C-200mg)
5 mL Clear Glass Sealed Ampule (890880C-25mg)

Application

18:0 TAP has been used in chloroform to prepare microbubbles.

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

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分析证书(COA)

Lot/Batch Number

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In vivo transfection and detection of gene expression of stem cells preloaded with DNA-carrying microbubbles
Tavri S, et al.
Radiology, 276(2), 518-525 (2015)
Yuki Takechi-Haraya et al.
Langmuir : the ACS journal of surfaces and colloids, 34(26), 7805-7812 (2018-06-06)
It has recently been recognized that the mechanical properties of lipid nanoparticles play an important role during in vitro and in vivo behaviors such as cellular uptake, blood circulation, and biodistribution. However, there have been no quantitative investigations of the
A E Regelin et al.
Biochimica et biophysica acta, 1464(1), 151-164 (2000-03-08)
In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)

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