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Merck
CN

900150O

Avanti

CoQ6

Avanti Research™ - A Croda Brand

Synonym(s):

Coenzyme Q6 (S. cerevisiae)

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About This Item

Empirical Formula (Hill Notation):
C39H58O4
CAS Number:
1065-31-2
Molecular Weight:
590.88
MDL number:
MFCD00055698
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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Product Name

CoQ6, Avanti Research™ - A Croda Brand 900150O

SMILES string

O=C(C(OC)=C1OC)C(C)=C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)C1=O

InChI

1S/C39H58O4/c1-28(2)16-11-17-29(3)18-12-19-30(4)20-13-21-31(5)22-14-23-32(6)24-15-25-33(7)26-27-35-34(8)36(40)38(42-9)39(43-10)37(35)41/h16,18,20,22,24,26H,11-15,17,19,21,23,25,27H2,1-10H3/b29-18+,30-20+,31-22+,32-24+,33-26+

InChI key

GXNFPEOUKFOTKY-LPHQIWJTSA-N

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mg (900150O-1mg)
pkg of 1 × 5 mg (900150O-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 900150O

lipid type

neutral glycerides
neutral lipids

shipped in

dry ice

storage temp.

−20°C

Application

CoQ6 has been used:
  • as an internal standard for the liquid-chromatography mass-spectrometry for the quantification of CoQ6
  • to determine its effect on peroxisome proliferator-activated receptor (PPAR)
  • in reversed-phase high pressure liquid chromatography to quantify yeast quinones

Biochem/physiol Actions

Coenzyme Q6 (CoQ6) in the plasma membrane of Saccharomyces cerevisiae is involved in the ascorbate stabilization at the plasma membrane.

General description

Coenzyme Q6 (CoQ6) is also known as ubiquinone-30 in Saccharomyces cerevisiae. It is a flavoprotein that utilizes flavin adenine dinucleotide (FAD) as a co-factor for the synthesis of coenzyme Q. It is composed of three conserved regions- a FAD/ nicotinamide adenine dinucleotide (NAD) + hydrogen (H) (NADH) binding motif, an adenine di phosphate (ADP) binding motif and a consensus sequence, that binds to the ribityl moiety of FAD.

Packaging

2 mL Amber Glass Sealed Ampule (900150O-1mg)
2 mL Amber Glass Sealed Ampule (900150O-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Idebenone and coenzyme Q10 are novel PPAR alpha gamma ligands, with potential for treatment of fatty liver diseases
Tiefenbach J, et al.
Disease models & mechanisms, 11(9) (2018)
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation
Spindler S R, et al.
PLoS ONE, 7(6) (2012)
CLD1 Reverses the Ubiquinone Insufficiency of Mutant cat5/coq7 in a Saccharomyces cerevisiae Model System
Kar A, et al.
PLoS ONE (2016)
CLD1 Reverses the Ubiquinone Insufficiency of Mutant cat5/coq7 in a Saccharomyces cerevisiae Model System
Kar A, et al.
Testing (2016)
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation
Spindler S R, et al.
Testing, 7(6) (2012)
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