产品名称
CoQ6, Avanti Research™ - A Croda Brand 900150O
SMILES string
O=C(C(OC)=C1OC)C(C)=C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)C1=O
InChI
1S/C39H58O4/c1-28(2)16-11-17-29(3)18-12-19-30(4)20-13-21-31(5)22-14-23-32(6)24-15-25-33(7)26-27-35-34(8)36(40)38(42-9)39(43-10)37(35)41/h16,18,20,22,24,26H,11-15,17,19,21,23,25,27H2,1-10H3/b29-18+,30-20+,31-22+,32-24+,33-26+
InChI key
GXNFPEOUKFOTKY-LPHQIWJTSA-N
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mg (900150O-1mg), pkg of 1 × 5 mg (900150O-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 900150O
lipid type
neutral glycerides
neutral lipids
shipped in
dry ice
storage temp.
−20°C
General description
Coenzyme Q6 (CoQ6) is also known as ubiquinone-30 in Saccharomyces cerevisiae. It is a flavoprotein that utilizes flavin adenine dinucleotide (FAD) as a co-factor for the synthesis of coenzyme Q. It is composed of three conserved regions- a FAD/ nicotinamide adenine dinucleotide (NAD) + hydrogen (H) (NADH) binding motif, an adenine di phosphate (ADP) binding motif and a consensus sequence, that binds to the ribityl moiety of FAD.
Application
CoQ6 has been used:
- as an internal standard for the liquid-chromatography mass-spectrometry for the quantification of CoQ6
- to determine its effect on peroxisome proliferator-activated receptor (PPAR)
- in reversed-phase high pressure liquid chromatography to quantify yeast quinones
Biochem/physiol Actions
Coenzyme Q6 (CoQ6) in the plasma membrane of Saccharomyces cerevisiae is involved in the ascorbate stabilization at the plasma membrane.
Packaging
2 mL Amber Glass Sealed Ampule (900150O-1mg)
2 mL Amber Glass Sealed Ampule (900150O-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
CLD1 Reverses the Ubiquinone Insufficiency of Mutant cat5/coq7 in a Saccharomyces cerevisiae Model System
Kar A, et al.
Testing (2016)
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation
Spindler S R, et al.
PLoS ONE, 7(6) (2012)
Idebenone and coenzyme Q10 are novel PPAR alpha gamma ligands, with potential for treatment of fatty liver diseases
Tiefenbach J, et al.
Disease models & mechanisms, 11(9) (2018)
CLD1 Reverses the Ubiquinone Insufficiency of Mutant cat5/coq7 in a Saccharomyces cerevisiae Model System
Kar A, et al.
PLoS ONE (2016)
Biosynthesis of coenzyme Q in eukaryotes
Kawamukai M
Bioscience, Biotechnology, and Biochemistry, 80(1), 23-33 (2016)
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