产品名称
CoQ6, Avanti Research™ - A Croda Brand 900150O
SMILES string
O=C(C(OC)=C1OC)C(C)=C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)C1=O
InChI
1S/C39H58O4/c1-28(2)16-11-17-29(3)18-12-19-30(4)20-13-21-31(5)22-14-23-32(6)24-15-25-33(7)26-27-35-34(8)36(40)38(42-9)39(43-10)37(35)41/h16,18,20,22,24,26H,11-15,17,19,21,23,25,27H2,1-10H3/b29-18+,30-20+,31-22+,32-24+,33-26+
InChI key
GXNFPEOUKFOTKY-LPHQIWJTSA-N
assay
>99% (TLC)
form
liquid
packaging
pkg of 1 × 1 mg (900150O-1mg)
pkg of 1 × 5 mg (900150O-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 900150O
lipid type
neutral glycerides
neutral lipids
shipped in
dry ice
storage temp.
−20°C
Application
CoQ6 has been used:
- as an internal standard for the liquid-chromatography mass-spectrometry for the quantification of CoQ6
- to determine its effect on peroxisome proliferator-activated receptor (PPAR)
- in reversed-phase high pressure liquid chromatography to quantify yeast quinones
Biochem/physiol Actions
Coenzyme Q6 (CoQ6) in the plasma membrane of Saccharomyces cerevisiae is involved in the ascorbate stabilization at the plasma membrane.
General description
Coenzyme Q6 (CoQ6) is also known as ubiquinone-30 in Saccharomyces cerevisiae. It is a flavoprotein that utilizes flavin adenine dinucleotide (FAD) as a co-factor for the synthesis of coenzyme Q. It is composed of three conserved regions- a FAD/ nicotinamide adenine dinucleotide (NAD) + hydrogen (H) (NADH) binding motif, an adenine di phosphate (ADP) binding motif and a consensus sequence, that binds to the ribityl moiety of FAD.
Packaging
2 mL Amber Glass Sealed Ampule (900150O-1mg)
2 mL Amber Glass Sealed Ampule (900150O-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation
Spindler S R, et al.
PLoS ONE, 7(6) (2012)
CLD1 Reverses the Ubiquinone Insufficiency of Mutant cat5/coq7 in a Saccharomyces cerevisiae Model System
Kar A, et al.
Testing (2016)
CLD1 Reverses the Ubiquinone Insufficiency of Mutant cat5/coq7 in a Saccharomyces cerevisiae Model System
Kar A, et al.
PLoS ONE (2016)
Idebenone and coenzyme Q10 are novel PPAR alpha gamma ligands, with potential for treatment of fatty liver diseases
Tiefenbach J, et al.
Disease models & mechanisms, 11(9) (2018)
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation
Spindler S R, et al.
Testing, 7(6) (2012)
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