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About This Item
Empirical Formula (Hill Notation):
C39H80 NO6 P
CAS Number:
Molecular Weight:
690.03
UNSPSC Code:
51191904
NACRES:
NA.25
Product Name
16:0-18:1 Diether PE, Avanti Research™ - A Croda Brand 999974P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (999974P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 999974P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[NH3+])(OC[C@]([H])(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCCCCCCCCCC)=O
InChI
1S/C39H80NO6P/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-35-44-39(38-46-47(41,42)45-36-33-40)37-43-34-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h17,19,39H,3-16,18,20-38,40H2,1-2H3,(H,41,42)/b19-17-/t39-/m1/s1
InChI key
QMGSXZBWJYQMDL-VEAYGOGPSA-N
General description
16:0-18:1 Diether PE or 1-O-hexadecanyl-2-O-(9Z-octadecenyl)-sn-glycero-3-phosphoethanolamine is a class of glycerophospholipids that have hexadecane and octadecene chains attached to the sn-1 and sn-2 positions of the glycerol backbone respectively by ether bonds. It has ethanolamine as the alcohol moiety, attached to the phosphate group.
Biochem/physiol Actions
Certain important signaling molecules are derived from ether linked phospholipids, which act as precursors. 20 percent of the total phospholipids in human are ether linked phospholipids. Inborn errors hindering the synthesis of ether phospholipids might lead to pathological conditions. Phosphoethanolamines (PEs) serve as a substrate for several phospholipids of the cell membrane. They are associated with the phospholipid turnover. PEs are also found to prevent tumor progression.
Packaging
5 mL Clear Glass Sealed Ampule (999974P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
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Ether-linked lipids and their bioactive species
Biochemistry of Lipids, Lipoproteins and Membranes, 245-276 (2008)
Adilson Kleber Ferreira et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 67(6), 481-487 (2013-06-19)
Phosphoethanolamine (Pho-s) is a compound involved in phospholipid turnover, acting as a substrate for many phospholipids of the cell membranes. In a recent study, we showed that Pho-s has antitumor effect in the several tumor cells. In this study we
John M Dean et al.
Protein & cell, 9(2), 196-206 (2017-05-20)
Ether lipids, such as plasmalogens, are peroxisome-derived glycerophospholipids in which the hydrocarbon chain at the sn-1 position of the glycerol backbone is attached by an ether bond, as opposed to an ester bond in the more common diacyl phospholipids. This
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 999974P-10MG | 04061835232550 |