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A-060

Amiodarone hydrochloride solution

Name: Amiodarone hydrochloride solution
Brand: CERILLIAN

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant^®

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About This Item

Empirical Formula (Hill Notation):

C₂₅H₃₀ClI₂NO₃

CAS Number:

19774-82-4

Molecular Weight:

681.77

UNSPSC Code:

41116107

MDL number:

MFCD00069204

NACRES:

NA.24

EC Number:

200-659-6

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Properties

grade

certified reference material

Quality Level

300

form

liquid

feature

SNAP-N-SPIKE^®, SNAP-N-SHOOT^®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

Cl.CCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3

InChI

1S/C25H29I2NO3.ClH/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3;/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3;1H

InChI key

ITPDYQOUSLNIHG-UHFFFAOYSA-N

Gene Information

human ... KCNH2(3757)

Description

General description

Amiodarone, marketed as Pacerone^®, Cordarone^®, Aratac, and Atlansil, is an antiarrhythmic agent monitored by clinical labs using HPLC or LCMS to ensure patients remain within the drugs therapeutic range.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Cordarone is a registered trademark of Sanofi S.A.

Pacerone is a registered trademark of Upsher-Smith Laboratories, Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS02,GHS06,GHS08

signalword

Danger

hcodes

H225,H301 + H311 + H331,H370

pcodes

P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Information

危险化学品

This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Protocols

LC/MS/MS Analysis of Interacting Cardiac Drugs Digoxin, Quinidine, Amiodarone and Verapamil on Titan™ C18

Single-Cell Analysis: Visualizing Pharmaceutical and Metabolite Uptake in Cells with Label-Free 3D Mass Spectrometry Imaging.

Melissa K Passarelli et al.

Analytical chemistry, 87(13), 6696-6702 (2015-05-30)

Detecting metabolites and parent compound within a cell type is now a priority for pharmaceutical development. In this context, three-dimensional secondary ion mass spectrometry (SIMS) imaging was used to investigate the cellular uptake of the antiarrhythmic agent amiodarone, a phospholipidosis-inducing

Global Trade Item Number

SKU	GTIN
SML4003-25MG	04065272154734
SML4003-5MG	04065272154741
A-060-1ML	04061833326183
44613-100ML	04061832284507