Skip to Content
Merck
CN

E-081

Etizolam solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C17H15ClN4S
CAS Number:
40054-69-1
Molecular Weight:
342.85
NACRES:
NA.24
PubChem Substance ID:
329798867
UNSPSC Code:
41116107
MDL number:
MFCD00867532

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C17H15ClN4S/c1-3-11-8-13-16(12-6-4-5-7-14(12)18)19-9-15-21-20-10(2)22(15)17(13)23-11/h4-8H,3,9H2,1-2H3

SMILES string

CCC1=CC2=C(S1)N3C(CN=C2C4=CC=CC=C4Cl)=NN=C3C

InChI key

VMZUTJCNQWMAGF-UHFFFAOYSA-N

grade

certified reference material

form

liquid

feature

(Snap-N-Spike®)

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland

Quality Level

300

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

Related Categories

General description

A certified solution standard for use in LC/MS or GC/MS benzodiazepine testing methods in clinical toxicology, urine drug testing, or forensic analysis. Etizolam, sold under brand names such as Etilaam, Etizola, or Depas, is a benzodiazepine analog used for the short-term treatment of insomnia, anxiety, or panic attacks. Etizolam is also sold on the designer drug market with cases of abuse noted in Europe and the US.

Biochem/physiol Actions

Etizolam is a thienodiazepine anxiolytic and as compared to other benzodiazepines has lower dependence potential. It differs from other benzodiazepines in that its molecules possess a thiophene ring instead of benzene. It has anticonvulsant, sedative, anxiolytic, amnesic, hypnotic and muscle relaxant properties. It′s mode of action is through benzodiazepine receptor. It is used to treat insomnia, moderate depression and social anxiety disorder, and has occasionally been associated with blepharospasm and skin lesions.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F

flash_point_c

9.7 °C

Regulatory Information

监管及禁止进口产品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Toshiaki Makino et al.
Biological & pharmaceutical bulletin, 28(2), 280-284 (2005-02-03)
Kamisyoyosan (KSS) and Tokisyakuyakusan (TSS) are widely used herbal formulas in Japanese traditional kampo medicine to relieve the symptoms occurred in climacteric disturbance. Since Japanese physicians frequently prescribe these formulas combined with etizolam, one of benzodiazepine anxiolytics, we evaluated the
Encyclopedia of Psychopharmacology
Ian Stolerman
Springer Science & Business Media, 502-502 (2010)
A Lopedota et al.
Journal of microencapsulation, 24(3), 214-224 (2007-04-25)
The aim of this study was to gain insight into the feasibility of using microparticles (MPs) constituted by the biodegradable poly (DL-lactide-co-glycolide) (PLGA) and a number of cyclodextrins (CDs) as an orally sustained delivery system of the hypnotic agent etizolam
Yutaro Suzuki et al.
Therapeutic drug monitoring, 26(6), 638-642 (2004-12-01)
Administration of fluvoxamine with concomitant benzodiazepines is common in clinical situations. This study investigated the effects of the coadministration of fluvoxamine on plasma concentrations of etizolam and evaluated the effects of various fluvoxamine doses on drug interactions with etizolam. Subjects
Inclusion of thienodiazepines in prescription rate of anxiolytics.
Katsuhiro Toda
Psychiatry and clinical neurosciences, 63(3), 430-430 (2009-07-02)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service