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Safety Information

I-035

Supelco

Insulin from bovine pancreas solution

100 μg/mL (PBS pH 7.2), certified reference material, ampule of 0.5 mL, Cerilliant®

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Empirical Formula (Hill Notation):
C254H377N65O75S6
CAS Number:
11070-73-8
Molecular Weight:
5733.49
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 0.5 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL (PBS pH 7.2)

technique(s)

liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

InChI key

IXIBAKNTJSCKJM-BUBXBXGNSA-N

Related Categories

General description

Bovine insulin differs from human insulin in three amino acid residues and is therefore used as internal standard for human insulin. This Certified Spiking Solution® of fully-intact bovine insulin protein is suitable for quantification of human insulin in LC-MS/MS insulin testing methods. Insulin is a peptide hormone, composed of 51 amino acids, produced by beta cells of the pancreatic islets. Insulin regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of, especially glucose from the blood into liver, fat and skeletal muscle cells. Insulin levels are routinely measured to evaluate insulin production; diagnose insulin-producing tumors; determine hypoglycemia or to identify insulin resistance.
This product is a certified reference material containing insulin solution of bovine origin. It is prepared and certified under ISO 17034, ISO/IEC 17025, ISO 9001, and ISO 13485 standards. This solution satisfies the primary standard and certified reference material classifications as determined by the ISO guidelines. The standard is created from a pure substance in an aqueous solvent solution. Insulin from bovine pancreas is available in phosphate buffered saline (PBS), pH 7.2 (solution).

Application

Insulin from bovine pancreas solution is suitable for the in vitro identification, calibration, and quantification of the analyte in analytical and R&D applications.

Features and Benefits

  • This standard is traceable to the SI and higher order standards from national institute of standards and technology (NIST) through an unbroken chain of comparisons.
  • Active insulin content is quantitatively determined using amino acid analysis (AAA) and chromatographic purity techniques.
  • No adjustment is necessary before use.
  • Every raw material incorporated into this product has undergone thorough identification and characterization using various analytical techniques and is assigned a Mass Balance Purity Factor.
  • The gravimetric preparation of this solution, including all balances and instruments, meets the ISO 17025 requirements for qualification and calibration.
  • The fill volume is gravimetrically verified using qualified and calibrated balances throughout the dispensing process, ensuring accuracy and consistency.

Preparation Note

  • Before use, thaw the product at room temperature or in a refrigerator and mix it thoroughly.
  • Avoid refreezing the product, once thawed.
  • Quantitatively transfer the required volume for spiking or dilution using established good laboratory practices.

Other Notes

This product′s purpose is for testing. THIS PRODUCT IS NOT INTENDED FOR HUMAN OR THERAPEUTIC USE. Refer to the safety data sheet for specific details regarding any potential hazards and necessary precautions.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

监管及禁止进口产品

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