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Merck
CN

M-129

(1R,2S)-(-)-N--Methylephedrine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

Ephedra

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About This Item

Empirical Formula (Hill Notation):
C11H17NO
CAS Number:
552-79-4
Molecular Weight:
179.26
NACRES:
NA.24
PubChem Substance ID:
329817865
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD00004504

Key Documents

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InChI key

FMCGSUUBYTWNDP-ONGXEEELSA-N

InChI

1S/C11H17NO/c1-9(12(2)3)11(13)10-7-5-4-6-8-10/h4-9,11,13H,1-3H3/t9-,11-/m0/s1

SMILES string

CC(C(O)c1ccccc1)N(C)C

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

Quality Level

300

Related Categories

General description

Methylephedrine, a sympathomimetic amine and a bronchodilator, is a component of several over-the-counter cough medications such as "BRON." Methylephedrine occasionally used in athletics as a performance enhancing drug for its stimulant effect. This Certified Snap-N-Spike® Solution is applicable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from sports testing and urine drug testing to forensic analysis and clinical toxicology.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

51.8 °F - closed cup

flash_point_c

11.0 °C - closed cup

Regulatory Information

监管及禁止进口产品
This item has

Certificates of Analysis (COA)

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Guoyi Ma et al.
The Journal of pharmacology and experimental therapeutics, 322(1), 214-221 (2007-04-05)
Ephedra species of plants have both beneficial and adverse effects primarily associated with the presence of ephedrine alkaloids. Few reports have appeared that examine the direct actions of ephedrine alkaloids on human subtypes of adrenergic receptors (ARs). In the present
Lin Zhu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 820(2), 175-182 (2005-05-19)
A selective and sensitive method has been developed and validated for simultaneous quantification of methylephedrine and noscapine in human plasma. Analytes were extracted from human plasma samples by liquid-liquid extraction, separated on a Diamonsil C18 column and detected by tandem
H J Lee et al.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 30(6), 563-566 (2010-08-13)
No information is currently available on the safety of methylephedrine, a component of various cold medications available in South Korea. With previous approval by an Institutional Review Board, 349 women inadvertently exposed to methylephedrine during the 1st trimester of pregnancy
Yan-Ming Liu et al.
Biomedical chromatography : BMC, 23(11), 1138-1144 (2009-06-06)
A novel method for the determination of ephedra alkaloids (methylephedrine and pseudoephedrine) was developed by electrophoresis capillary (CE) separation and electrochemiluminesence detection (ECL). The use of ionic liquid (1-butyl-3-methylimidazolium tetrafluoroborate, BMIMBF(4)) improved the detection sensitivity markedly. The conditions for CE
Yan-Ming Liu et al.
Electrophoresis, 30(8), 1406-1411 (2009-03-19)
A new approach for the determination of methylephedrine hydrochloride (ME), thebaine, codeine phosphate (CP), and acetylcodeine (AC) was established by CE-ECL with ionic liquid (1-butyl-3-methylimidazolium tetrafluoroborate). The conditions for the CE separation, ECL detection, and the effect of ionic liquid
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