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Merck
CN

M-919

Supelco

Mianserin hydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C18H21ClN2
CAS Number:
21535-47-7
Molecular Weight:
300.83
EC Number:
200-659-6
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol (as free base)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

Cl.CN1CCN2C(C1)c3ccccc3Cc4ccccc24

InChI

1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H

InChI key

YNPFMWCWRVTGKJ-UHFFFAOYSA-N

General description

Mianserin is a tetracyclic antidepressant prescribed for the treatment of depression and is sold under the trade names Lumin and Tolvon. This certified solution standard is applicable for use in LC/MS or GC/MS applications for urine drug testing, clinical toxicology, and forensic analysis. This tetracyclic antidepressant functions as a noradrenergic and a specific serotonergic antidepressant with anxiolytic, hypnotic, antiemetic, orexigenic, and antihistamine effects.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Clinical practice. Chronic pruritus.
Gil Yosipovitch et al.
The New England journal of medicine, 368(17), 1625-1634 (2013-04-26)
Marij Zuidersma et al.
Journal of psychosomatic research, 74(1), 25-30 (2013-01-01)
Evaluating the effects of implementing an antidepressant treatment strategy in depressed myocardial infarction (MI)-patients on long-term cardiovascular outcomes and all-cause mortality. MI-patients were evaluated for the presence of a diagnosis of post-MI depression at 3, 6, 9 and 12months after
Eveline Jaquenoud Sirot et al.
Journal of clinical psychopharmacology, 32(5), 622-629 (2012-08-29)
Pharmacogenetic tests and therapeutic drug monitoring may considerably improve the pharmacotherapy of depression. The aim of this study was to evaluate the relationship between the efficacy of mirtazapine (MIR) and the steady-state plasma concentrations of its enantiomers and metabolites in
Renee Romeo et al.
The British journal of psychiatry : the journal of mental science, 202, 121-128 (2012-12-22)
Depression is a common and costly comorbidity in dementia. There are very few data on the cost-effectiveness of antidepressants for depression in dementia and their effects on carer outcomes. To evaluate the cost-effectiveness of sertraline and mirtazapine compared with placebo
E L Theunissen et al.
Clinical pharmacology and therapeutics, 93(6), 493-501 (2013-04-17)
The aim of this study was to assess the effects of a novel antidepressant, vortioxetine 10 mg, on driving, cognitive, and psychomotor performance in 24 healthy subjects in a double-blind, placebo-controlled, three-way crossover design. Mirtazapine 30 mg was included as an active
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