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S-010

Sildenafil solution

Name: Sildenafil solution
Brand: CERILLIAN

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

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About This Item

Empirical Formula (Hill Notation):

C₂₂H₃₀N₆O₄S

CAS Number:

139755-83-2

Molecular Weight:

474.58

NACRES:

NA.24

PubChem Substance ID:

329824411

UNSPSC Code:

41116107

EC Number:

200-659-6

MDL number:

MFCD00867528

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grade

certified reference material

Quality Level

300

form

liquid

feature

Snap-N-Spike^®/Snap-N-Shoot^®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant^®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

pharmaceutical (small molecule)

format

single component solution

storage temp.

−20°C

SMILES string

O=C1NC(C2=C(OCC)C=CC(S(=O)(N3CCN(C)CC3)=O)=C2)=NC4=C1N(C)N=C4CCC

InChI

1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)

InChI key

BNRNXUUZRGQAQC-UHFFFAOYSA-N

Gene Information

human ... PDE5A(8654)

Related Categories

Analytical Chemistry

Certified Reference Materials

Controlled Substances & Illicit Drug Standards

Reference Materials

General description

Sildenafil is a treatment for erectile dysfunction and pulmonary arterial hypertension. Sold under the trade name Viagra^®, sildenafil has a history of abuse, including by athletes as a performance enhancing drug. This Certified Spiking Solution^® is applicable for use in urine drug testing, sports testing, clinical toxicology or forensic analysis by LC-MS/MS or GC/MS.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Viagra is a registered trademark of Pfizer, Inc.

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

pictograms

GHS02,GHS06,GHS08

signalword

Danger

hcodes

H225,H301 + H311 + H331,H370

pcodes

P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Information

危险化学品

This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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[Yesterday, Viagra was a medication].

Jean-Yves Nau

Revue medicale suisse, 9(392), 1396-1397 (2013-07-26)

Pharmacokinetic comparison of an orally disintegrating film formulation with a film-coated tablet formulation of sildenafil in healthy Korean subjects: a randomized, open-label, single-dose, 2-period crossover study.

Hyerang Roh et al.

Clinical therapeutics, 35(3), 205-214 (2013-03-19)

An orally disintegrating film (ODF) formulation of sildenafil was recently developed in Korea. This formulation is expected to enhance dosing convenience and increase patient compliance while yielding pharmacokinetics comparable to those of the conventional film-coated tablet (FCT) formulation. The goal

[The prescription].

Jürgen Rabe

MMW Fortschritte der Medizin, 155(1), 28-28 (2013-04-12)

Appraisal of sildenafil binding on the structure and promiscuous esterase activity of native and histidine-modified forms of carbonic anhydrase II.

Hamid Mahdiuni et al.

Biophysical chemistry, 175-176, 1-16 (2013-03-19)

Sildenafil was investigated for its interaction with the native and modified human carbonic anhydrase II (hCA II). Modification of exposed histidine side chains with diethyl pyrocarbonate decreased esterase activity of the enzyme. The treatment of both native and modified CA

[Yesterday, Viagra was a drug (2) ].