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Safety Information

V-010

Supelco

(±)-α-Tocopherol-D6 (Vitamin E-D6) solution

500 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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Empirical Formula (Hill Notation):
C29H44D6O2
CAS Number:
Molecular Weight:
436.74
MDL number:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

(Snap-N-Spike®
Snap-N-Shoot®)

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

500 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

-97.99 °C

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−20°C

General description

It is the deuterated form of α-tocopherol, a form of fat-soluble vitamin E.

Application

This stable-labeled Certified Spiking Solution® is suitable for quantifying a-tocopherol in a variety of applications from diagnostic testing of Vitamin E deficiency to quality control testing of tocopherol-based dietary supplements or pharmaceutical preparations.

The certified reference material (CRM) in solution can also be used as an internal standard as follows:
  • High-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) based combined analysis of retinol, α‐tocopherol, 25‐hydroxyvitamin D2, and 25‐hydroxyvitamin in plasma samples of cardiovascular patients
  • Simultaneous determination of 25-hydroxyvitamin-D2 (25-OHD2), 25-hydroxyvitamin-D3 (25-OHD3), and its 3-epimer (epi-25-OHD3), retinol, and α-tocopherol in human serum samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
  • Development of two ultra and high-performance liquid chromatographic methods, one coupled with atmospheric pressure chemical ionization and tandem mass spectrometric detector (UHPLC-APCI-MS/MS) and the other one with diode array detector (HPLC-DAD) to estimate fat-soluble vitamins A, D3 and E in rice cereal-based baby food samples
  • Multi-residue analysis of fat-soluble vitamins (FSVs)― retinol, 25(OH)D2, 25(OH)D3, epi-25(OH)D3. and α-tocopherol in plasma and amniotic fluid samples by liquid chromatography-tandem mass spectrometry (LC-MS/MS) following a single pre-treatment step

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup

Regulatory Information

危险化学品

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