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Merck
CN

V-040

Retinyl acetate solution

100 μg/mL in ethanol (with 0.1% (w/v) BHT; degassed), reference material, Cerilliant®

Synonym(s):

Vitamin A acetate solution

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About This Item

Empirical Formula (Hill Notation):
C22H32O2
CAS Number:
127-47-9
Molecular Weight:
328.49
UNSPSC Code:
41116107
PubChem Substance ID:
329828975
NACRES:
NA.24
MDL number:
MFCD00019413

Key Documents

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SMILES string

O(C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(CCCC1(C)C)C)C(=O)C

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

grade

reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in ethanol (with 0.1% (w/v) BHT; degassed)

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−70°C

Quality Level

200

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General description

Retinyl acetate, a natural preform of vitamin A, is classified as generally recognized as safe in the amounts used to fortify foods with vitamin A and is especially recommended for maternal supplementation during pregnancy.

Application

Retinyl acetate solution may be used as a certified reference material (CRM) for the determination of the analyte in biological samples, dairy foods and pharmaceutical formulations by chromatography techniques.
This certified solution standard is suitable for use as an internal standard in chromatographic or MS-based methods in clinical testing applications such as assessment of vitamin A deficiency or in food and nutrition testing applications of vitamin A supplements and fortified foods.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

hcodes

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

57.2 °F - closed cup

flash_point_c

14.0 °C - closed cup

Regulatory Information

危险化学品
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Simultaneous determination of ?-tocopherol and retinol in plasma or red cells by high pressure liquid chromatography
Bieri JG, et al.
American Journal of Clinical Nutrition, 32(10), 2143-2149 (1979)
Simultaneous liquid chromatographic determination of vitamins A, E and ?-carotene in common dairy foods
Hewavitharana AK, et al.
International dairy journal, 6(6), 613-624 (1996)
Determination of retinoids in human serum, tocopherol and retinyl acetate in pharmaceuticals by RP-LC with electrochemical detection
Wang LH and Wang JF
Journal of Pharmaceutical and Biomedical Analysis, 25(5-6), 785-793 (2001)

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