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Merck
CN

V-044

Vitamin K2-(MK-7)

100 μg/mL in acetonitrile, certified reference material, Cerilliant®

Synonym(s):

(all-E)–2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione

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About This Item

Empirical Formula (Hill Notation):
C46H64O2
CAS Number:
2124-57-4
Molecular Weight:
649.00
UNSPSC Code:
12352205
NACRES:
NA.24

Key Documents

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SMILES string

O=C1c2c(cccc2)C(=O)C(=C1C\C=C(\CC\C=C(\CC\C=C(\CC\C=C(\CC\C=C(\CC\C=C(\CCC=C(C)C)/C)/C)/C)/C)/C)/C)C

InChI

1S/C46H64O2/c1-34(2)18-12-19-35(3)20-13-21-36(4)22-14-23-37(5)24-15-25-38(6)26-16-27-39(7)28-17-29-40(8)32-33-42-41(9)45(47)43-30-10-11-31-44(43)46(42)48/h10-11,18,20,22,24,26,28,30-32H,12-17,19,21,23,25,27,29,33H2,1-9H3/b35-20+,36-22+,37-24+,38-26+,39-28+,40-32+

InChI key

RAKQPZMEYJZGPI-LJWNYQGCSA-N

grade

certified reference material

Quality Level

300

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

mp

-48 °C

format

single component solution

shipped in

wet ice

storage temp.

−70°C

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General description

Vitamin K2 (MK-7), also known as menaquinone-7, is a homolog of Vitamin K2. Reports suggest that supplementation of Vitamin K2 (MK-7) can improve bone strength and prevent bone loss.

Application

This Certified Spiking Solution® is suitable for use as starting material in the preparation of linearity standards, calibrators, or controls in LC-MS/MS vitamin K2 testing applications such as assessment of vitamin K2 deficiency and detection and quantification of vitamin K2 in food or nutritional products
Vitamin K2 (MK-7) may be used as a certified reference material (CRM) for the determination of the analyte in biological samples and fermented foods by high performance liquid chromatography methods.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2.0 °C - closed cup

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A novel salting-out assisted extraction coupled with HPLC-fluorescence detection for trace determination of vitamin K homologues in human plasma
Ahmed S and Mahmoud AM
Talanta, 144(7-8), 480-487 (2015)
Simultaneous determination of vitamin K analogs in human serum by sensitive and selective high-performance liquid chromatography with electrochemical detection
Wakabayashi H, et al.
Nutrition, 19(7-8), 661-665 (2003)
Determination of vitamin K composition of fermented food
Tarvainen M, et al.
Food Chemistry, 275(3), 515-522 (2019)
Method for the determination of vitamin K homologues in human plasma using high-performance liquid chromatography-tandem mass spectrometry
Suhara Y, et al.
Analytical Chemistry, 77(3), 757-763 (2005)

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