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Merck
CN

V-067

(−)-Riboflavin

100 μg/mL (1% ammonium acetate in 50:50 methanol:water), certified reference material, ampule of 1 mL, Cerilliant®

Synonym(s):

Lactoflavin, Vitamin B2, Vitamin G

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About This Item

Empirical Formula (Hill Notation):
C17H20N4O6
CAS Number:
83-88-5
Molecular Weight:
376.36
UNSPSC Code:
12352205
NACRES:
NA.24
Beilstein/REAXYS Number:
07825

Key Documents

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Product Name

(−)-Riboflavin, 100 μg/mL (1% ammonium acetate in 50:50 methanol:water), certified reference material, ampule of 1 mL, Cerilliant®

InChI

1S/C17H20N4O6/c1-7-3-9-10(4-8(7)2)21(5-11(23)14(25)12(24)6-22)15-13(18-9)16(26)20-17(27)19-15/h3-4,11-12,14,22-25H,5-6H2,1-2H3,(H,20,26,27)/t11-,12+,14-/m0/s1

SMILES string

O[C@H]([C@H](O)[C@H](O)CO)CN1C2=CC(C)=C(C)C=C2N=C3C1=NC(NC3=O)=O

InChI key

AUNGANRZJHBGPY-SCRDCRAPSA-N

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL (1% ammonium acetate in 50:50 methanol:water)

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

290 °C (dec.)

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

Quality Level

300

Related Categories

Application

Riboflavin (vitamin B2) may be used as a certified reference material (CRM) for the determination of the analyte in foodstuffs, biological samples and pharmaceuticals by different chromatography techniques.
This certified solution standard is suitable for use as starting materials in the preparation of calibrators, controls, or linearity standards in a variety of testing applications from diagnostic testing of vitamin B2 deficiency by HPLC to quality control testing of vitamin B2-based dietary supplements, fortified foods or pharmaceutical preparations.

General description

Riboflavin is an essential B vitamin for maintaining human health with key roles in energy metabolism as well as a critical component of enzyme cofactors and flavoproteins.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

75.2 °F

flash_point_c

24 °C

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

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Determination of thiamine, riboflavin and pyridoxine in pharmaceuticals by synchronous fluorescence spectrometry in organized media
Garc?a L, et al.
Analytica Chimica Acta, 434(2), 193-199 (2001)
Determination of riboflavin in urine by capillary electrophoresis--blue light emitting diode-induced fluorescence detection combined with a stacking technique
Su An-Kai and Lin Cheng-Huang
Journal of Chromatography. B, Biomedical Sciences and Applications, 785(1), 39-46 (2003)
Rapid determination of thiamine, riboflavin, niacinamide, pantothenic acid, pyridoxine, folic acid and ascorbic acid in Vitamins with Minerals Tablets by high-performance liquid chromatography with diode array detector
Jin P, et al.
Journal of Pharmaceutical and Biomedical Analysis, 70(2), 151-157 (2012)
Chromatographic determination of riboflavin and its derivatives in food
Gliszczynska-Swiglo A and Koziolowa A
Journal of Chromatography A, 881(1-2), 285-297 (2000)
Determination of riboflavin and flavin mononucleotide in foodstuffs using high-performance liquid chromatography and a column-enrichment technique
Lumley ID and Wiggins RA
Analyst, 106(1267), 1103-1108 (1981)
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