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Merck
CN

03-0134-00

SMC® Mouse IL-10 Discovery Immunoassay Kit

Used for ultrasensitive quantification of Mouse IL-10 in mouse serum and plasma.

Synonym(s):

mouse IL 10 immunoassay kit, mouse IL-10 Single Molecule Counting Kit, mouse IL-10 ultra-sensitive immunoassay, mouse Interleukin 10 immunoassay kit

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000
Species reactivity:
mouse
Technique(s):
single molecule counting: suitable
Usage:
 kit sufficient for 96 wells
Compatibility:
for use with Erenna instrument

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Quality Level

200

technique(s)

single molecule counting: suitable

input

plasma (K2 EDTA)
serum

UniProt accession no.

P18893

compatibility

for use with Erenna instrument

shipped in

wet ice

product line

SMC®

usage

 kit sufficient for 96 wells

species reactivity

mouse

Related Categories

General description

Interleukin-10 (IL-10) is a cytokine with both stimulatory and suppressive effects on the immune system. The protein originates from several cell lines, including Th2 cells, mast cells, macrophages, monocytes and B-cells. Its main functions are to impede inflammatory responses and to inhibit synthesis of other pro-inflammatory cytokines, such as IL-2, IL-3, GM-CSF, IFN-γ and TNF-α. Besides its anti-inflammatory capabilities, IL-10 also regulates the production of natural killer cells and lymphocytes. Due to its multiple roles, proper function of IL-10 is required to maintain a healthy immune system. Improper function of IL-10 can result in disease development, as over expression of IL-10 has been linked to lymphoma, whereas IL-10 deficiency has implications for Crohn′s disease.

Application

Inflammatory Disease / Immune Response / Autoimmune Disease

Features and Benefits

  • Ultra-Sensitive Detection of Mouse IL-10: Enables quantification of low-abundance IL-10 in mouse serum, ideal for early immune response studies, inflammation models, and cytokine profiling.
  • Specificity for Biologically Active IL-10: Provides accurate and selective measurement of IL-10, supporting mechanistic studies in immunoregulation and disease modeling.
  • Ideal for Inflammation and Autoimmunity Research: IL-10 is a key anti-inflammatory cytokine involved in regulating Th1/Th2 balance, macrophage activity, and cytokine suppression. This kit supports disease modeling in Crohn’s, colitis, and lymphoma, where IL-10 dysregulation is implicated.

Packaging

96 well assay

Analysis Note

  • Standard Curve Range: 1500-1,500,000 fg/mL
  • Intra-assay CV: <15%
  • Inter-assay CV: <20%
  • Recovery: 80-120%

Legal Information

SMC is a registered trademark of Singulex

Disclaimer

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Hazard Classifications

Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1

Regulatory Information

新产品
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