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Safety Information

03-0146-00

Millipore

SMC® Amyloid Beta 42 High Sensitivity Kit

1 kit sufficient for 96 wells, input: serum, plasma, cerebrospinal fluid (CSF)

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Synonym(s):
Abeta 1-42 immunoassay kit, Abeta 42 Single Molecule Counting Kit, Abeta 42 immunoassay kit, Abeta 42 ultra-sensitive Immunoassay

Quality Level

200

usage

 kit sufficient for 96 wells

species reactivity

human, rat, mouse

manufacturer/tradename

SMC®

assay range

sensitivity: 0.98 pg/mL
(lower limit of quantification)
inter-assay cv: <20%
intra-assay cv: <15%
standard curve range: 0.24-250 pg/mL

technique(s)

ELISA: suitable
single molecule counting: suitable

input

serum
plasma
cerebrospinal fluid (CSF)

compatibility

for use with SMCxPRO® and Erenna<TMSYMBOL></TMSYMBOL> (validated)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

General description

The SMC® Amyloid β1-42 High Sensitivity Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format.

Assay protocols are similar to existing sandwich ELISA methods with two key differences:
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2)The Erenna and SMCxPRO® immunoassay systems detect analytes using Single Molecule Counting (SMC®) technology.

Specificity

The capture antibody recognizes the C-terminal end of Amyloid beta 1-42, conferring specificity for Aβ42. No significant cross-reactivity to Aβ38 and Aβ40 was observed.

Legal Information

SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation

Target Organs

Respiratory Tract

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Regulatory Information

含少量动物源组分生物产品
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Chia-Liang Tsai et al.
Journal of clinical medicine, 8(10) (2019-10-09)
Nondemented people with a family history of Alzheimer's disease (ADFH) and the ApoE-4 allele have been demonstrated to show a trend for a higher probability of cognitive decline and aberrant levels of cognitive-related biomarkers. However, the potential interactive effects on

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