Skip to Content
Merck
CN

03-0153-00

SMC® Glucagon High Sensitivity Immunoassay Kit

Used for ultrasensitive quantification of Glucagon in human, rat or mouse plasma

Synonym(s):

Glucagon Single Molecule Counting Kit, Glucagon ultra-sensitive immunoassay, Pro-glucagon immunoassay kit

Sign In to View Organizational & Contract Pricing.

Select a Size


About This Item

NACRES:
NA.84
UNSPSC Code:
12161503
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

SMC® Glucagon High Sensitivity Immunoassay Kit, Used for ultrasensitive quantification of Glucagon in human, rat or mouse plasma

product line

SMC®

usage

 kit sufficient for 96 wells

quality

200

species reactivity

human, mouse, rat

manufacturer/tradename

SMC®

technique(s)

single molecule counting: suitable

input

plasma (K2 EDTA)

UniProt accession no.

compatibility

for use with FemtoQuest and SMCxPRO® instruments

shipped in

wet ice

storage temp.

2-8°C

Disclaimer

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Legal Information

SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany

Analysis Note

Metabolism
Endocrinology
  • Sensitivity: LLOQ 781 fg/mL* (SMCxPRO® Instrument)
  • Standard Curve Range: 200-200,000 fg/mL
  • Intra-assay CV: <15%
  • Inter-assay CV: <20%
  • Linearity: Plasma: 86%
  • Recovery: Plasma: 86%
  • *Indicative LLOQ created from average of 14 independent in house runs,where >80% met same value defined with CV & Recovery +/- 20%. Refer toCoA for lot specific performance.

Application

Metabolism

Biochem/physiol Actions

Glucagon (human) was found to be 100% detectable.
Oxyntomodulin (human) was found to be <0.5% detectable.
GLP-1 (human) was not found to be detectable.
GLP-2 (human) was not found to be detectable.
GIP (human) was not found to be detectable.

Features and Benefits

  • Ultra-Sensitive Detection — Quantifies glucagon down to 0.20 pg/mL
  • Wide Dynamic Range — Covers 0.20–200 pg/mL
  • SMC® Technology — Enables single molecule resolution for precise quantification
  • Species Compatibility — Validated for human, mouse, and rat plasma
  • Detect Glucagon at Femto-Level Sensitivity — Ideal for metabolic and endocrine research
  • Reliable Across Species — Supports translational studies from animal models to human samples
  • Accurate Results with Minimal Interference — Trusted data in complex biological fluids

Packaging

96 well assay

General description

Glucagon is a peptide hormone secreted by pancreatic alphacells that plays a vital role in maintaining glucose homeostasis. It acts as acounter-regulatory hormone to insulin by stimulating glycogenolysis andgluconeogenesis in the liver, thereby increasing blood glucose levels duringfasting or hypoglycemia. In addition to its role in glucose metabolism,glucagon also influences lipid metabolism and energy balance, making it a keybiomarker in metabolic and endocrine research.

Altered glucagon levels are associated with metabolicdisorders such as type 2 diabetes, obesity, and insulin resistance. Accuratemeasurement of glucagon is essential for understanding pancreatic function,evaluating therapeutic interventions, and studying the hormonal regulation ofenergy metabolism.

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation

target_organs

Respiratory Tract

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Regulatory Information

新产品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Related Content

Explore ultrasensitive immunoassay technology with SMC® technology, including its biomarker detection platform, advantages of high sensitivity assays, and more.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service