产品名称
SMC®人IL-17F高灵敏度试剂盒,
description
Used for ultrasensitive quantification of Human IL-17F in human serum and plasma
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
technique(s)
single molecule counting: suitable
input
plasma (K2 EDTA)
serum
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments
shipped in
wet ice
storage temp.
2-8°C
General description
SMC®人IL-17F高灵敏度免疫分析试剂盒包含进行分析所需的所有试剂。该测定采用以标准孔板形式配置的标准免疫测定工作流程。
测定方案与现有的夹心ELISA方法相似,但有两个主要区别:
1)洗脱缓冲液破坏夹心结构,分离标记的检测抗体以进行定量。
2)Erenna 和SMCxPRO® 免疫测定系统使用单分子计数(SMC®)技术对分析物进行检测。
测定方案与现有的夹心ELISA方法相似,但有两个主要区别:
1)洗脱缓冲液破坏夹心结构,分离标记的检测抗体以进行定量。
2)Erenna 和SMCxPRO® 免疫测定系统使用单分子计数(SMC®)技术对分析物进行检测。
Application
Inflammatory Disease / Immune Response / Autoimmune Disease
Features and Benefits
- Detect the Undectable: Detects IL-17F at concentrations as low as 200 fg/mL, enabling precise quantification of low-abundance cytokines in human plasma and serum.
- Wide Dynamic Range: Standard curve spans 100-100,000 fg/mL, supporting both basal and elevated IL-17F levels in diverse sample types.
- Advance Th17 Pathway Research: IL-17F is a critical cytokine in autoimmune and inflammatory diseases such as asthma, psoriasis, and IBD. This assay supports mechanistic studies and therapeutic development.
- Enable Early Biomarker Discovery: Detect subclinical cytokine shifts with high sensitivity, ideal for identifying early disease markers and monitoring immune responses.
Packaging
96 well assay
Analysis Note
- Sensitivity: LLOQ 200 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 100-100,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 99% Plasma: 101%
- Recovery: Serum: 94% Plasma: 105%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Other Notes
Although IL-17F was detectable in non-human primate samples, the assay has not been verified for these species.
Legal Information
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
我们的产品仅用于研究目的,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用对人类或动物。
signalword
Danger
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B

