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Merck
CN

03-0164-00

SMC®人IL-17F高灵敏度试剂盒

Used for ultrasensitive quantification of Human IL-17F in human serum and plasma

别名:

IL-17F Single Molecule Counting Kit, IL-17F ultra-sensitive immunoassay, IL17F immunoassay kit, Interleukin-17F immunoassay kit

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UNSPSC代码:
12161503
NACRES:
NA.84

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产品线

SMC®

用途

 kit sufficient for 96 wells

种属反应性

human

制造商/商品名称

SMC®

技术

single molecule counting: suitable

输入

plasma (K2 EDTA)
serum

UniProt登记号

Q96PD4

相容性

for use with FemtoQuest™ and SMCxPRO® instruments

运输

wet ice

储存温度

2-8°C

相关类别

一般描述

SMC®人IL-17F高灵敏度免疫分析试剂盒包含进行分析所需的所有试剂。该测定采用以标准孔板形式配置的标准免疫测定工作流程。

测定方案与现有的夹心ELISA方法相似，但有两个主要区别：
1）洗脱缓冲液破坏夹心结构，分离标记的检测抗体以进行定量。
2）Erenna 和SMCxPRO® 免疫测定系统使用单分子计数（SMC®）技术对分析物进行检测。

应用

Inflammatory Disease / Immune Response / Autoimmune Disease

生化/生理作用

已发现可检测非人类灵长类动物样品。 尽管可以检测到IL-17F，但尚未对此物种的测定进行验证。

特点和优势

  • Detect the Undectable: Detects IL-17F at concentrations as low as 200 fg/mL, enabling precise quantification of low-abundance cytokines in human plasma and serum.
  • Wide Dynamic Range: Standard curve spans 100-100,000 fg/mL, supporting both basal and elevated IL-17F levels in diverse sample types.
  • Advance Th17 Pathway Research: IL-17F is a critical cytokine in autoimmune and inflammatory diseases such as asthma, psoriasis, and IBD. This assay supports mechanistic studies and therapeutic development.
  • Enable Early Biomarker Discovery: Detect subclinical cytokine shifts with high sensitivity, ideal for identifying early disease markers and monitoring immune responses.

包装

96 well assay

分析说明

  • Sensitivity: LLOQ 200 fg/mL* (SMCxPRO® Instrument
  • Standard Curve Range: 100-100,000 fg/mL
  • Intra-assay CV: <15%
  • Inter-assay CV: <20%
  • Linearity: Serum: 99% Plasma: 101%
  • Recovery: Serum: 94% Plasma: 105%

*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Inflammation & ImmunologyInflammatory DiseaseImmune ResponseAutoimmune Disease

法律信息

FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

我们的产品仅用于研究目的，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用对人类或动物。

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

法规信息

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